Study Results from National Health Insurance Service Ilsan Hospital Provide New Insights into Cesarean Section (Effect of Maternal Age On Maternal and Perinatal Outcomes Including Cesarean Delivery Following Induction of Labor In Uncomplicated …): Surgery – Cesarean Section

2021 SEP 24 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Women’s Health Daily -- Data detailed on Surgery - Cesarean Section have been presented. According to news reporting originating from Gyeonggi-do, South Korea, by NewsRx correspondents, research stated, “Age above 35 years at the time of birth is generally referred to as advanced maternal age (AMA), and it could be a risk factor for various complications besides genetic changes in the fetus. The primary outcome of this study was to determine if AMA is associated with emergent cesarean delivery (CD) following induction of labor (IOL).”

Financial support for this research came from National Health Insurance Service Ilsan Hospital.

Our news editors obtained a quote from the research from National Health Insurance Service Ilsan Hospital, “The secondary outcomes were a composite of adverse maternal and perinatal outcomes following IOL. This retrospective observational study included women with singleton, live-born, cephalic, non-anomalous pregnancies undergoing IOL from 38 0/7 to 41 6/7 weeks of gestation. Mode of delivery and other maternal and neonatal outcomes were compared between women aged >= 35 (AMA) and <35 years. Multivariate logistic regression analyses were performed. A total of 307 nulliparous women underwent IOL (>= 35 years n = 73, 23.8%; <35 years n = 234, 76.2%) and among them, 252 (82.1%) delivered vaginally. The rate of CD was significantly higher in women of AMA (31.5% vs 13.7%, P = .001). Multivariable analysis showed that AMA was independently associated with CD (odds ratio 3.04, 95% confidence interval 1.55-5.96, P = .001). The rate of instrumental deliveries was higher in the AMA group (19.6% vs 8.2%, P = .043) and hemoglobin decrease during delivery was similar between the 2 groups (1.90 +/- 1.25 vs 2.02 +/- 1.27 mg/dL, all P> .05). Regarding neonatal outcomes, there was no difference between the 2 groups in the neonatal intensive care unit admission rate and Apgar score <7 at 5 minutes (30.3% vs 30.1% and 6.0% vs 8.2%, respectively, all P> .05). Neonatal intubation rate and severe respiratory problems were non-significantly higher in AMA (3.8% vs 2.7% and 3.4% vs 1.4%, respectively, all P> .05). AMA was associated with an approximately three-fold increased likelihood of birth by CD and operative vaginal delivery in uncomplicated nulliparous women following IOL.”

According to the news editors, the research concluded: “However, we found no evidence that IOL in primigravid women of AMA increases adverse maternal and perinatal outcomes as compared with women aged <35 years except the high prevalence of CD and operative vaginal delivery.”

For more information on this research see: Effect of Maternal Age On Maternal and Perinatal Outcomes Including Cesarean Delivery Following Induction of Labor In Uncomplicated Elderly Primigravidae. Medicine, 2021;100(34). Medicine can be contacted at: Lippincott Williams & Wilkins, Two Commerce Sq, 2001 Market St, Philadelphia, PA 19103, USA. (Elsevier - www.elsevier.com; Medicine - http://www.journals.elsevier.com/medicine/)

The news editors report that additional information may be obtained by contacting Eui Hyeok Kim, National Health Insurance Service Ilsan Hospital, Dept. of Obstetrics and Gynecology, 100 Ilsan Ro, Goyang Si 10444, Gyeonggi Do, South Korea. Additional authors for this research include Yeonseong Jeong, Sung Pil Choo and Jisun Yun.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1097/MD.0000000000027063. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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