Study Findings from University College Broaden Understanding of Health and Medicine [Protocol for the economic evaluation of a community-based…

Study Findings from University College Broaden Understanding of Health and Medicine [Protocol for the economic evaluation of a community-based intervention to improve growth among children under two in rural India (CARING trial)]

By a News Reporter-Staff News Editor at Clinical Trials Week -- Current study results on Health and Medicine have been published. According to news originating from London, United Kingdom, by NewsRx correspondents, research stated, "Undernutrition affects ∼165 million children globally and contributes up to 45% of all child deaths. India has the highest proportion of global undernutrition-related morbidity and mortality."

Funders for this research include Wellcome Trust, Medical Research Council, Department for International Development (see also Health and Medicine).

Our news journalists obtained a quote from the research from University College, "This protocol describes the planned economic evaluation of a community-based intervention to improve growth in children under 2 years of age in two rural districts of eastern India. The intervention is being evaluated through a cluster-randomised controlled trial (cRCT, the CARING trial). A cost-effectiveness and cost-utility analysis nested within a cRCT will be conducted from a societal perspective, measuring programme, provider, household and societal costs. Programme costs will be collected prospectively from project accounts using a standardised tool. These will be supplemented with time sheets and key informant interviews to inform the allocation of joint costs. Direct and indirect costs incurred by providers will be collected using key informant interviews and time use surveys. Direct and indirect household costs will be collected prospectively, using time use and consumption surveys. Incremental cost-effectiveness ratios (ICERs) will be calculated for the primary outcome measure, that is, cases of stunting prevented, and other outcomes such as cases of wasting prevented, cases of infant mortality averted, life years saved and disability-adjusted life years (DALYs) averted. Sensitivity analyses will be conducted to assess the robustness of results. There is a shortage of robust evidence regarding the cost-effectiveness of strategies to improve early child growth. As this economic evaluation is nested within a large scale, cRCT, it will contribute to understanding the fiscal space for investment in early child growth, and the relative (in)efficiency of prioritising resources to this intervention over others to prevent stunting in this and other comparable contexts."

According to the news editors, the research concluded: "The protocol has all necessary ethical approvals and the findings will be disseminated within academia and the wider policy sphere."

For more information on this research see: Protocol for the economic evaluation of a community-based intervention to improve growth among children under two in rural India (CARING trial). Bmj Open, 2016;6(11):e012046. (BMJ Publishing Group - group.bmj.com/; Bmj Open - bmjopen.bmj.com/)

The news correspondents report that additional information may be obtained from J. Skordis-Worrall, University College London, Institute for Global Health, London, UK. Additional authors for this research include R. Sinha, A. Kumar Ojha, S. Sarangi, N. Nair, P. Tripathy, H.S. Sachdev, S. Bhattacharyya, R. Gope, S. Rath, S. Rath, A. Srivastava, N. Batura, A.M. Pulkki-Brannstrom, A. Costello, A. Copas, N. Saville and .

Keywords for this news article include: London, Europe, United Kingdom, Health and Medicine.

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