Researchers at Korea University Target Acute Pyelonephritis (Trend of antibiotics usage for acute pyelonephritis in Korea based on national health insurance data 2010-2014)

2019 JUL 22 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Business Daily -- Investigators publish new report on Urologic Diseases and Conditions - Acute Pyelonephritis. According to news reporting out of Seoul, South Korea, by NewsRx editors, research stated, “The objective of this study is to describe the changes in prescribing practices of antibiotics to treat acute pyelonephritis (APN) in Korea. The claim data base of the Health Insurance Review and Assessment Service in Korea was used to select patients with ICD-10 codes N10 (acute tubulo-interstitial nephritis) or N12 (tubulo-interstitial nephritis, not specified as acute nor chronic) as the primary discharge diagnosis during 2010-2014.”

Financial support for this research came from Korea Health Industry Development Institute.

Our news journalists obtained a quote from the research from Korea University, “Consumption of each class of antibiotics was converted to Defined Daily Dose (DDD)/event. Throughout the five-year period, the average antibiotic consumption were 11.3 DDD per inpatient event and 6.0 DDD per outpatient event. The annual average antibiotic consumption increased for inpatients (p=0.002), but remained stable for outpatients (p=0.066). The use of parenteral antibiotics increased for inpatients (p <0.001), but decreased for outpatients (p=0.017). As for the the antibiotic classes, 3 generation cephalosporins (3 CEPs) was the most commonly prescribed (41.4%) for inpatients, followed by fluoroquinolones (FQs) (28.5%); for outpatient, FQs (54.8%) was the most commonly prescribed, followed by 3 CEPs (13.1%). The use of 3 CEPs (p <0.001), beta-lactam/beta-lactamase inhibitors (p=0.007), and carbapenems (p <0.001) increased substantially for the treatment of hospitalized APN patients. In particular, carbapenems use increased 3.1-fold over the 5 years.”

According to the news editors, the research concluded: “Prescription of broad-spectrum antibiotics increased much for the treatment of APN in Korea during 2010-2014.”

For more information on this research see: Trend of antibiotics usage for acute pyelonephritis in Korea based on national health insurance data 2010-2014. Bmc Infectious Diseases, 2019;19(1):554. (BioMed Central - http://www.biomedcentral.com/; Bmc Infectious Diseases - http://www.biomedcentral.com/bmcinfectdis/)

Our news journalists report that additional information may be obtained by contacting M.J. Lee, Dept. of Economics, College of Political Science & Economics, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, South Korea. Additional authors for this research include R. Myung, M.J. Lee, J. Kim and H. Pai.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1186/s12879-019-4191-0. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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