Research Results from Kangwon National University School of Medicine Update Knowledge of Cerebrovascular Disease (Cardiovascular Risks in Korean Patients with Gout: Analysis Using a National Health Insurance Service Database): Central Nervous System Diseases and Conditions – Cerebrovascular Disease

2022 MAY 05 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Business Daily -- Research findings on cerebrovascular disease are discussed in a new report. According to news reporting out of Chuncheon, South Korea, by NewsRx editors, research stated, “Although several epidemiologic studies have shown the association between gout and cardiovascular outcomes, specific risk factors for developing cardiovascular diseases in Asian patients with gout are undisclosed. Thus, the purpose of this study was to investigate risks of cardiovascular outcomes and its related factors in Korean patients with gout.”

Financial supporters for this research include Patient-Centered Clinical Research Coordinating Center Award: HI19C0481, HC21C0010.

The news journalists obtained a quote from the research from Kangwon National University School of Medicine: “This retrospective clinical study used sampled cohort data from the National Health Insurance Service in Korea. Patients with gout were defined as subjects enlisted with an ICD-10 code (M10). Control patients were selected by frequency matching for age, sex, and index year. Primary outcomes included ischemic heart disease (IHD), congestive heart failure, cerebrovascular disease (CVD), or transient ischemic attack. We calculated the hazard ratio (HR) using Cox regression, adjusting potential confounders including age, sex, lifestyle habits, laboratory results, and medication. We identified 3306 patients with gout and an equal number of matched controls. Multivariate Cox regression analysis showed that gout patients had increased risks of IHD (HR: 1.860, 95% CI: 1.446-2.392), acute myocardial infarction (HR: 3.246, 95% CI: 1.460-7.217), and CVD (HR: 1.552, 95% CI: 1.177-2.036).”

According to the news reporters, the research concluded: “Old age, current smoking, frequent alcohol intake, high low-density lipoprotein, and diabetes mellitus increased the risk of cardiovascular outcomes, yet hypouricemic agents decreased the risk of cerebrovascular diseases. Our data corroborate that it is crucial to identify and manage traditional cardiovascular risk factors alongside lowering urate levels in patients with gout.”

For more information on this research see: Cardiovascular Risks in Korean Patients with Gout: Analysis Using a National Health Insurance Service Database. Journal of Clinical Medicine, 2022,11(2124):2124. (Journal of Clinical Medicine - http://www.mdpi.com/journal/jcm). The publisher for Journal of Clinical Medicine is MDPI AG.

A free version of this journal article is available at https://doi.org/10.3390/jcm11082124.

Our news editors report that additional information may be obtained by contacting Ki Won Moon, Division of Rheumatology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24289, South Korea. Additional authors for this research include Min Jung Kim, In Ah Choi, Kichul Shin. Our reports deliver fact-based news of research and discoveries from around the world.