New Hepatitis C Virus Study Findings Recently Were Reported by V. Lo Re and Co-Researchers (Disparities in Absolute Denial of Modern Hepatitis C…

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New Hepatitis C Virus Study Findings Recently Were Reported by V. Lo Re and Co-Researchers (Disparities in Absolute Denial of Modern Hepatitis C Therapy by Type of Insurance)

By a News Reporter-Staff News Editor at Insurance Weekly News -- Current study results on Liver Diseases and Conditions have been published. According to news reporting originating from Philadelphia, Pennsylvania, by VerticalNews correspondents, research stated, "The high costs of direct-acting antiviral (DAA) agents to treat chronic hepatitis C virus (HCV) infection have resulted in denials of treatment, but it is not clear whether patients' access to these therapies differs with their type of insurance. We conducted a prospective cohort study among all patients who had a DAA prescription submitted between November 1, 2014 and April 30, 2015 to Burman's Specialty Pharmacy, which provides HCV pharmacy services to patients in Delaware, Maryland, New Jersey, and Pennsylvania."

Our news editors obtained a quote from the research, "We determined the incidence of absolute denial of DAA prescription, defined as a lack of approval of a prescription fill by the insurer, according to type of insurance (US Medicaid, US Medicare, or commercial insurance). Multivariable Poisson regression was used to estimate adjusted relative risks of absolute denial associated with patient characteristics. Among 2321 patients prescribed a DAA regimen (503 covered by Medicaid, 795 covered by Medicare, and 1023 covered by commercial insurance), 377 (16.2%) received an absolute denial. The most common reasons for absolute denial were insufficient information to assess medical need (134 [35.5%]) and lack of medical necessity (132 [35.0%]). A higher proportion of patients covered byMedicaid received an absolute denial (233 [46.3%]) than those covered by Medicare (40 [5.0%]; P< .001) or commercial insurance (104 [10.2%]; P< .001). Medicaid insurance (adjusted relative risk, 4.14; 95% confidence interval, 3.38-5.08) and absence of cirrhosis (adjusted relative risk, 1.96; 95% confidence interval, 1.53-2.50) were associated with absolute denial. There are significant disparities in access to DAA-based treatments for HCV infection among patients with different types of insurance."

According to the news editors, the research concluded: "Nearly half of Medicaid beneficiaries in Delaware, Maryland, New Jersey, and Pennsylvania were denied access to these drugs for chronic HCV infection."

For more information on this research see: Disparities in Absolute Denial of Modern Hepatitis C Therapy by Type of Insurance. Clinical Gastroenterology and Hepatology, 2016;14(7):1035-1043. Clinical Gastroenterology and Hepatology can be contacted at: Elsevier Science Inc, 360 Park Ave South, New York, NY 10010-1710, USA. (Elsevier - www.elsevier.com; Clinical Gastroenterology and Hepatology - www.journals.elsevier.com/clinical-gastroenterology-and-hepatology/)

The news editors report that additional information may be obtained by contacting V. Lo Re, Philadelphia Field Initiating Grp HIV Trials, John Bell Hlth Center, Philadelphia, PA, United States. Additional authors for this research include C. Gowda, P.N. Urick, J.T. Halladay, A. Binkley, D.M. Carbonari, K. Battista, C. Peleckis, J. Gilmore, J.A. Roy, J.A. Doshi, P.P. Reese, K.R. Reddy and J.R. Kostman.

Keywords for this news article include: Philadelphia, Pennsylvania, United States, North and Central America, Liver Diseases and Conditions, Digestive System Diseases, Flaviviridae Infections, Infectious Disease, Hepatitis C Virus, Gastroenterology, Liver Diseases, Health Policy, RNA Viruses, Medicare, Medicaid, Hepatology, Virology, Therapy, Viral, HCV.