New Bursitis Study Findings Recently Were Reported by Researchers at Soochow University (Hyperlipidemia Is a Risk Factor of Adhesive Capsulitis: Real-world Evidence Using the Taiwanese National Health Insurance Research Database)

2021 MAY 12 (NewsRx) -- By a News Reporter-Staff News Editor at Information Technology Business Daily -- Investigators publish new report on Musculoskeletal Diseases and Conditions - Bursitis. According to news reporting originating in Taipei, Taiwan, by NewsRx journalists, research stated, “Patients with adhesive capsulitis are evaluated for pain and progressive contracture of the glenohumeral joint. Whether endocrine, immune, or inflammatory processes are involved in its definite pathogenesis is still under debate.”

The news reporters obtained a quote from the research from Soochow University, “Some cross-sectional studies with a small sample size have noted that hyperlipidemia is a possible risk factor for frozen shoulders. Purpose/Hypothesis: The purpose was to conduct a longitudinal population-based study to investigate the risk of adhesive capsulitis among patients with hyperlipidemia. It was hypothesized that patients with hyperlipidemia would have a higher risk of adhesive capsulitis and that the use of statin drugs could reduce the rate. Cohort study; Level of evidence, 3. Using data from the National Health Insurance Research Database (NHIRD) of Taiwan, the authors obtained the records of patients with hyperlipidemia who received a diagnosis between 2004 and 2005 and were followed up until the end of 2010. The control cohort comprised age- and sex-matched patients without hyperlipidemia. Propensity score matching was performed for the other comorbidities. A Cox multivariate proportional hazards model was applied to analyze the risk factors of adhesive capsulitis. The hazard ratio (HR) and adjusted HR were estimated between the study and control cohorts after adjustment for confounders. The effects of statin use on adhesive capsulitis risk were also analyzed. The NHIRD records of 28,748 patients and 114,992 propensity score-matched controls were evaluated. A higher incidence rate of adhesive capsulitis was revealed in the hyperlipidemia cohort, with a crude HR of 1.70 (95% CI, 1.61-1.79; P< .001) and adjusted HR of 1.50 (95% CI, 1.41-1.59; P< .001). Patients with hyperlipidemia who used a statin still had higher crude and adjusted HRs compared with controls. Statin use did not exert protective effects on patients with hyperlipidemia. Patients with hyperlipidemia had a 1.5-fold higher risk of adhesive capsulitis than did healthy controls.”

According to the news reporters, the research concluded: “Statin use did not provide protection against adhesive capsulitis in patients with hyperlipidemia.”

For more information on this research see: Hyperlipidemia Is a Risk Factor of Adhesive Capsulitis: Real-world Evidence Using the Taiwanese National Health Insurance Research Database. Orthopaedic Journal of Sports Medicine, 2021;9(4):232596712098680. Orthopaedic Journal of Sports Medicine can be contacted at: Sage Publications Inc, 2455 Teller Rd, Thousand Oaks, CA 91320, USA.

Our news correspondents report that additional information may be obtained by contacting Hui-Wen Lin, Soochow University, Taipei, Taiwan. Additional authors for this research include Jr-Yi Wang, Chen-Kun Liaw, Chi-Chang Huang, Tsan-Hon Liou and Shih-Wei Huang.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1177/2325967120986808. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

(Our reports deliver fact-based news of research and discoveries from around the world.)