Neuroscience Institute Researchers Report Research in Stroke (Predictors of Post-Stroke Depression: A Retrospective Cohort Study): Cerebrovascular Diseases and Conditions – Stroke

2022 SEP 12 (NewsRx) -- By a News Reporter-Staff News Editor at Insurance Daily News -- New study results on stroke have been published. According to news reporting originating from Danville, Pennsylvania, by NewsRx correspondents, research stated, “Despite reports of a high incidence and various predictors of post-stroke depression (PSD), the underdiagnosis and undertreatment rates of PSD are still high. This study aimed to examine the incidence of depression in stroke patients and identify factors associated with PSD.”

The news reporters obtained a quote from the research from Neuroscience Institute: “This was a retrospective cohort study on ischemic stroke patients from the Geisinger Neuroscience Ischemic Stroke (GNSIS) registry. The following statistical analyses were performed to predict PSD in the studied population: a Kaplan-Meier estimator and a Cox proportional hazards model. A total of 5882 patients were included in the study. The median age at the time of an ischemic stroke was 72 years and 56% were males. A total of 294 patients were diagnosed with PSD within one year of a stroke. The cumulative incidence of depression was found to be 6.4% (95% CI 5.7-7.1%) at one year for the entire cohort. Women were found to have a higher risk of PSD than men (HR for women = 1.47, 95% CI 1.18-1.85, * * p* * = 0.001). A history of prior stroke (HR = 1.58, 95% CI 1.18-2.11, * * p* * = 0.002) and myocardial infarction (HR = 1.47, 95% CI 1.05-2.06, * * p* * = 0.025) were associated with PSD. Medicaid patients had a higher risk for PSD (HR = 2.16, 95% CI 1.5-3.12, * * p* * < 0.001) than those with commercial insurance or health maintenance organization plans.”

According to the news editors, the research concluded: “Our findings showed that women, patients with a history of prior stroke or myocardial infarction, and with Medicaid insurance were more likely to develop PSD. Through an observational study on the EHR data, we confirmed that chronic stress, including financial and health-related stress, irrespective of age, significantly increased the risk for PSD.”

For more information on this research see: Predictors of Post-Stroke Depression: A Retrospective Cohort Study. Brain Sciences, 2022,12(993):993. (Brain Sciences - http://www.mdpi.com/journal/brainsci/). The publisher for Brain Sciences is MDPI AG.

A free version of this journal article is available at https://doi.org/10.3390/brainsci12080993.

Our news journalists report that more information may be obtained by contacting Durgesh Chaudhary, Department of Neurology, Neuroscience Institute, Geisinger Health System, Danville, PA 17822, United States. Additional authors for this research include Isabel Friedenberg, Vishakha Sharma, Pragyan Sharma, Vida Abedi, Ramin Zand, Jiang Li.

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