Korea University Anam Hospital Reports Findings in Acid Reflux Disease (Association of preterm birth with medications: machine learning analysis using national health insurance data): Digestive System Diseases and Conditions – Acid Reflux Disease

Engineering Business Daily

2022 JAN 31 (NewsRx) -- By a News Reporter-Staff News Editor at Engineering Business Daily -- New research on Digestive System Diseases and Conditions - Acid Reflux Disease is the subject of a report. According to news reporting from Seoul, South Korea, by NewsRx journalists, research stated, “To use machine learning and population data for testing the associations of preterm birth with socioeconomic status, gastroesophageal reflux disease (GERD) and medication history including proton pump inhibitors, sleeping pills and antidepressants. Population-based retrospective cohort data came from Korea National Health Insurance Service claims data for all women who aged 25-40 years and gave births for the first time as singleton pregnancy during 2015-2017 (405,586 women).”

The news correspondents obtained a quote from the research from Korea University Anam Hospital, “The dependent variable was preterm birth during 2015-2017 and 65 independent variables were included (demographic/socioeconomic determinants, disease information, medication history, obstetric information). Random forest variable importance (outcome measure) was used for identifying major determinants of preterm birth and testing its associations with socioeconomic status, GERD and medication history including proton pump inhibitors, sleeping pills and antidepressants. Based on random forest variable importance, major determinants of preterm birth during 2015-2017 were socioeconomic status (645.34), age (556.86), proton pump inhibitors (107.61), GERD for the years 2014, 2012 and 2013 (106.78, 105.87 and 104.96), sleeping pills (97.23), GERD for the years 2010, 2011 and 2009 (95.56, 94.84 and 93.81), and antidepressants (90.13). Preterm birth has strong associations with low socioeconomic status, GERD and medication history such as proton pump inhibitors, sleeping pills and antidepressants.”

According to the news reporters, the research concluded: “For preventing preterm birth, appropriate medication would be needed alongside preventive measures for GERD and the promotion of socioeconomic status for pregnant women.”

This research has been peer-reviewed.

For more information on this research see: Association of preterm birth with medications: machine learning analysis using national health insurance data. Archives of Gynecology and Obstetrics, 2022. Archives of Gynecology and Obstetrics can be contacted at: Springer Heidelberg, Tiergartenstrasse 17, D-69121 Heidelberg, Germany. (Springer - www.springer.com; Archives of Gynecology and Obstetrics - http://www.springerlink.com/content/0932-0067/)

Our news journalists report that additional information may be obtained by contacting In-Seok Song, Dept. of Oral and Maxillofacial Surgery, Korea University Anam Hospital, Seoul, South Korea. Additional authors for this research include Kwang-Sig Lee, Eun Sun Kim, Hae-In Kim and Ki Hoon Ahn.

Publisher contact information for the journal Archives of Gynecology and Obstetrics is: Springer Heidelberg, Tiergartenstrasse 17, D-69121 Heidelberg, Germany.

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