Tokushima Bunri University Reports Findings in Information Technology (Statin persistence and adherence among older initiators: A nationwide cohort study using the national health insurance claims database in Japan): Information Technology

2023 APR 17 (NewsRx) -- By a News Reporter-Staff News Editor at Information Technology Business Daily -- New research on Information Technology is the subject of a report. According to news reporting from Kagawa, Japan, by NewsRx journalists, research stated, “This study clarifies the reality of persistence and adherence to statins in older Japanese people who initiated statin use and compares it between primary and secondary prevention cohorts. The nationwide study using the national claims database targeted statin initiators aged 55 years from FY2014 to FY2017 in Japan.”

The news correspondents obtained a quote from the research from Tokushima Bunri University, “Persistence and adherence to statins were analyzed overall and according to subgroups based on sex, age stratum, and prevention cohorts. Permissible gap of median days that statins were supplied per prescription to an individual was employed. Persistence rates were estimated as Kaplan-Meier estimates. Poor adherence during persistence was evaluated and defined as <0.8 of the proportion of days covered. Of 3 675 949 initiators, approximately 80% initiated statin use with strong variants. The persistence rate at 1 year was 0.61. Poor adherence to statins during persistence was 8.0% in all patients and this value gradually improved with increasing age. Persistence rate and adherence were lower for the primary prevention cohort than for the secondary prevention cohort, and a notable sex difference was observed for the secondary prevention cohort, which was lower in females but was almost never and slightly observed in the primary prevention cohorts without and with high-risk factors, respectively. Many statin initiators discontinued statins shortly following statin initiation but adherence while on statin therapy was good.”

According to the news reporters, the research concluded: “Attentively watching older patients not to discontinue statins and listening to their reasons for discontinuation are required, especially for initiators in primary prevention and females in secondary prevention.”

This research has been peer-reviewed.

For more information on this research see: Statin persistence and adherence among older initiators: A nationwide cohort study using the national health insurance claims database in Japan. Pharmacoepidemiology and Drug Safety, 2023. Pharmacoepidemiology and Drug Safety can be contacted at: Wiley, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - http://www.wiley.com/; Pharmacoepidemiology and Drug Safety - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1099-1557)

Our news journalists report that additional information may be obtained by contacting Tomoji Yoshida, Faculty of Health and Welfare, Tokushima Bunri University, 1314-1 Shido, Sanuki, Kagawa, 769-2193, Japan. Additional authors for this research include Junko Tomida, Shoichi Senda, Tsugumichi Sato, Akira Nakatsuma and Naomi Iihara.

Publisher contact information for the journal Pharmacoepidemiology and Drug Safety is: Wiley, 111 River St, Hoboken 07030-5774, NJ, USA.

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