Study Data from Federal University Update Understanding of Hepatorenal Syndrome (Terlipressin versus noradrenaline in the treatment of hepatorenal…

Study Data from Federal University Update Understanding of Hepatorenal Syndrome (Terlipressin versus noradrenaline in the treatment of hepatorenal syndrome: systematic review with meta-analysis and full economic evaluation)

By a News Reporter-Staff News Editor at Insurance Weekly News -- Data detailed on Liver Diseases and Conditions have been presented. According to news reporting originating from Porto Alegre, Brazil, by VerticalNews correspondents, research stated, "The aim of this study was to compare the efficacy and costs of terlipressin and noradrenaline for the treatment of hepatorenal syndrome from the perspective of the Brazilian public health system and that of a major private health insurance. Comparison of efficacy was performed through a systematic review with a meta-analysis of randomized-controlled trials using a random-effects model."

Our news editors obtained a quote from the research from Federal University, "Economic evaluation was carried out through cost minimization. Four studies (154 patients) were included in the meta-analysis. There was no evidence of a difference between treatments with terlipressin or noradrenaline in terms of 30-day survival (risk ratio=1.04, 95% confidence interval=0.84-1.30, P=0.70). From the perspective of the public health system, costs of the treatments with terlipressin or noradrenaline were Int$7437.04 and Int$8406.41, respectively. From the perspective of the private health insurance, costs of treatments with terlipressin and noradrenaline were Int$13 484.57 and Int$15 061.01, respectively."

According to the news editors, the research concluded: "There was no evidence of superiority between treatment strategies using terlipressin or noradrenaline in terms of the survival of patients with hepatorenal syndrome, but the strategy using terlipressin was more economical under two different perspectives."

For more information on this research see: Terlipressin versus noradrenaline in the treatment of hepatorenal syndrome: systematic review with meta-analysis and full economic evaluation. European Journal of Gastroenterology & Hepatology, 2016;28(3):345-351. European Journal of Gastroenterology & Hepatology can be contacted at: Lippincott Williams & Wilkins, Two Commerce Sq, 2001 Market St, Philadelphia, PA 19103, USA. (Lippincott Williams and Wilkins - www.lww.com; European Journal of Gastroenterology & Hepatology - journals.lww.com/eurojgh/pages/default.aspx)

The news editors report that additional information may be obtained by contacting A.Z. de Mattos, Univ Fed Rio Grande do Sul, Postgraduate Course Epidemiol, Porto Alegre, RS, Brazil. Additional authors for this research include A.A. de Mattos and R.A. Ribeiro.

Keywords for this news article include: Brazil, Porto Alegre, South America, Public Health, Health Insurance, Hepatorenal Syndrome, Digestive System Diseases, Liver Diseases and Conditions

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2016, NewsRx LLC