Stroke treatments safe and effective for people with existing disability or dementia
Statement highlights:
- A research review found that clot-busting therapy and mechanical clot removal to treat ischemic stroke in people with a pre-existing disability or dementia was as safe and effective as in adults without those conditions. These treatments are key to preventing additional disability.
- A person's pre-existing disabilities or dementia may cloud the stroke assessment process, which may lead to clinicians thinking the stroke is more severe and beyond the window for optimal treatment. This often results in delayed treatment or no treatment.
- People with a disability or dementia should be included in randomized controlled trials for stroke treatment. Currently, evidence-based stroke treatment data and guidance for people with disability or dementia are extremely limited.
The statement reports that people with preexisting disability and dementia often experience delays in having their stroke symptoms recognized. In addition, when being assessed, the challenges of their disabilities or dementia may cloud the stroke assessment process, which may lead to clinicians thinking the stroke is more severe and beyond the window for optimal treatment. This often results in delayed treatment or no treatment, which, in turn may lead to additional disabilities and less likelihood to return to pre-stroke levels of daily living skills.
"The long-term consequences and costs of additional disabilities due to untreated stroke in people with pre-existing neurological deficits are staggering," said
Some evidence suggests people with pre-stroke dementia or disability also have a higher risk of death after clot-busting medications for stroke, however, the findings are inconsistent and require additional research. The statement notes that treatment risk is unique for each individual and would be higher for people with preexisting disability or dementia who have had previous microbleeds or white matter damage in the brain, visible on brain imaging such as a CT or MRI.
Several biases, such as ableism or therapeutic nihilism (believing there's no hope for effective treatment), may influence health care decision-making when considering stroke treatment for people with a disability or dementia. The writing group suggests increased awareness of potential biases and the statement's guidance may help physicians improve patient-centered stroke care for all people including those who have a pre-existing disability or dementia.
In the
The statement offers an approach to care for people with disability or dementia that includes discussions about treatment options and personal priorities and preferences for stroke care. Providers should:
- Prior to a stroke, discuss quality of life concerns and future care preferences with individuals with a disability or dementia and their families and develop plans for potential health emergencies including stroke.
- Examine personal biases that may influence decisions about treatment under time-pressured situations.
- Discuss individual risks and avoid routinely withholding stroke treatment to people with a disability or dementia.
- Understand the benefits of treatment in reducing risks for additional disability and other long-term impacts.
- Following a stroke, acknowledge the spectrum of possible outcomes - not just "good" or "bad" - and discuss the uncertainty about treatment effects, including the higher potential risk of death compared to people without existing disability or dementia, with the individual and their family.
- Adopt patient-centered care: Seek to understand individual's values, goals and beliefs that may affect care after a stroke, recognizing these values will vary by individual and are influenced by age, ethnicity, religious beliefs and more.
The statement also calls for inclusion of people with disability or dementia in stroke research and more information about how to balance the uncertain benefits and risks of therapy when caring for people with a disability or dementia.
"The people carrying the greatest burden of illness have been traditionally excluded from research," said Goyal. "Expansion of the dialogue and pro-active research on acute stroke therapies should include people with disability and dementia - to optimize their potential to return to their pre-stroke daily living and to reduce the potential long-term care and financial burdens."
The statement was developed by the volunteer writing committee on behalf of the
The writing committee includes Chair
The Association receives funding primarily from individuals. Foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and biotech companies, device manufacturers and health insurance providers and the Association's overall financial information are available here.
Additional Resources:
- Available multimedia is on right column of release link https://newsroom.heart.org/news/stroke-treatments-safe-and-effective-for-people-with-existing-disability-or-dementia?preview=6fe049e801e1461363a43e01cfb9870d
- After
March 28 , view the manuscript online - AHA policy statement: New recommendations for stroke systems of care to improve patient outcomes (
May 2019 ) - AHA/ASA Guidelines: More stroke patients may receive crucial treatments under new guidelines (
January 2018 ) - Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update (
October 2019 ) - AHA/ASA health information: Ischemic stroke treatment
- Follow AHA/ASA news on Twitter @HeartNews
- Follow news from Stroke, the ASA/AHA journal @StrokeAHA_ASA
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