Researchers from Kaohsiung Medical University Hospital Report on Findings in Alzheimer Disease (Urinary Incontinence in Alzheimer’s Disease)

Mental Health Weekly Digest

By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- A new study on Neurodegenerative Diseases and Conditions - Alzheimer Disease is now available. According to news reporting out of Kaohsiung, Taiwan, by NewsRx editors, research stated, "Urinary incontinence (UI) is more prevalent in the elderly populations with dementia than without dementia, and Alzheimer's disease (AD) is the most common cause of dementia. Urinary incontinence may complicate AD morbidity and mortality."

Our news journalists obtained a quote from the research from Kaohsiung Medical University Hospital, "Therefore, this study aimed to evaluate the prevalence and annual incidence and determine the risk possibility of UI, which is the main type of incontinence in patients with AD in Taiwan. A total of 933 patients with AD were included in the study cohort, and a total of 2799 patients without AD by 1:3 proportion compared to the study cohort were used as a matched cohort. All participants were selected from the National Health Insurance Research Database in 2000 sample population. We utilize Cox proportional hazard regression to evaluate the risk of UI and cumulative incidence ratio curve to analyze the cumulative incidence function. Prevalence and annual incidence rate are calculated in individual medication including rivastigmine, donepezil, galantamine, and memantine only being initiated in patients with AD. The risk of UI is higher in AD cohort (hazard ratio: 1.54, 95% confidence interval: 1.13-2.09). The cumulative incidence ratio of UI event between AD cohort and matched cohort presents statistical significance (p <.001). Annual incidence and prevalence of UI in patients with AD are 6.2% and 4.2%, respectively."

According to the news editors, the research concluded: "The present results suggest that the risk of UI is higher in patients with AD than in the general population."

For more information on this research see: Urinary Incontinence in Alzheimer's Disease. American Journal of Alzheimer's Disease and Other Dementias, 2016;32(1):51-55. American Journal of Alzheimer's Disease and Other Dementias can be contacted at: SAGE Publications, USA , 2455 Teller Road, Thousand Oaks, CA 91320, USA. (Sage Publications - www.sagepub.com/; American Journal of Alzheimer's Disease and Other Dementias - aja.sagepub.com)

Our news journalists report that additional information may be obtained by contacting H.Y. Lee, 1 Dept. of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Additional authors for this research include C.C. Li, Y.S. Juan, Y.H. Chang, H.C. Yeh, C.C. Tsai, K.S. Chueh, W.J. Wu and Y.H Yang (see also Neurodegenerative Diseases and Conditions - Alzheimer Disease).

Publisher contact information for the American Journal of Alzheimer's Disease and Other Dementias is: SAGE Publications, USA , 2455 Teller Road, Thousand Oaks, CA 91320, USA.

Keywords for this news article include: Asia, Taiwan, Dementia, Kaohsiung, Tauopathies, Alzheimer Disease, Urinary Incontinence, Brain Diseases and Conditions, Urologic Diseases and Conditions, Neurodegenerative Diseases and Conditions, Central Nervous System Diseases and Conditions.