Research Data from F. Hoffmann-La Roche Update Understanding of HIV/AIDS (Real-world Hiv Diagnostic Testing Patterns In the United States): Immune System Diseases and Conditions – HIV/AIDS

2022 MAR 24 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Business Daily -- Researchers detail new data in Immune System Diseases and Conditions - HIV/AIDS. According to news reporting out of Pleasanton, California, by NewsRx editors, research stated, “To understand real-world implementation of the updated CDC HIV diagnostic testing algorithm. Retrospective database analysis.”

Financial support for this research came from Roche Molecular Systems, Inc.

Our news journalists obtained a quote from the research from F. Hoffmann-La Roche, “Using data from Quest Diagnostics, we identified patients with at least 1 HIV-1/HIV-2 antibody differentiation test (BioRad Geenius HIV 1/2 Supplemental Assay [Geenius]) between January 1 and December 31, 2017. Study measures included Health Insurance Portability and Accountability Act-compliant patient demographics, test results, test frequency, and sequence relative to the CDC HIV diagnostic algorithm, including HIV-1 RNA Qualitative Assay (Aptima) or HIV-2 nucleic acid test (NAT). A total of 26,319 patients were identified (mean [SD] age, 40.7 [14.3] years; 66.4% male), with 28,954 Geenius tests, 7234 Aptima tests, and 298 HIV-2 NATs. In 26.4% of test sequences, the Geenius results were indeterminate or negative and required subsequent confirmatory NATs. A total of 8.5% of patients had more than 1 Geenius test in 2017, and 11.2% of the time, results of the first and second tests differed. A total of 74.2% of test sequences matched the CDC-recommended algorithm. Our study findings suggest that the CDC HIV diagnostic algorithm is complex and may pose suboptimal testing efficiency.”

According to the news editors, the research concluded: “Opportunities to improve diagnostic efficiency by reducing indeterminate results and repeat tests are warranted.”

This research has been peer-reviewed.

For more information on this research see: Real-world Hiv Diagnostic Testing Patterns In the United States. The American Journal of Managed Care, 2022;28(2). The American Journal of Managed Care can be contacted at: Managed Care & Healthcare Communications Llc, 666 Plainsboro Rd, Ste 300, Plainsboro, NJ 08536, USA.

Our news journalists report that additional information may be obtained by contacting James K. Karichu, F. Hoffmann-La Roche, Global Access & Hlth Econ, Pleasanton, CA 94588, United States. Additional authors for this research include Chakkarin Burudpakdee, Aimee M. Near, Jenny Tse, Jillian Faccone, Pedro L. Rodriguez and Mindy M. Cheng.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.37765/ajmc.2022.88826. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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