Reports on Graves Disease from China Medical University Provide New Insights (Association Between Haemorrhoids and Graves’ Disease: a Retrospective Cohort Study Using Data From Taiwan’s Longitudinal Health Insurance Database): Autoimmune Diseases and Conditions – Graves Disease

2022 JAN 26 (NewsRx) -- By a News Reporter-Staff News Editor at Insurance Daily News -- Researchers detail new data in Autoimmune Diseases and Conditions - Graves Disease. According to news reporting originating from Taichung, Taiwan, by NewsRx correspondents, research stated, “To evaluate the relationship between haemorrhoids and Graves’ disease (GD). Using the nationwide data from Taiwan’s Longitudinal Health Insurance Database.”

Funders for this research include Taiwan Ministry of Health and Welfare Clinical Trial Center, China Medical University Hospital, Ministry of Science and Technology.

Our news editors obtained a quote from the research from China Medical University, “We conducted a retrospective study, stratified patients by International Classification of Diseases, Ninth Revision, Clinical Modification disease code and compared the incidence rate of GD between patients with and without haemorrhoids. The study period was from 2000 to 2010, with exclusion of patients with diagnosed haemorrhoids before 2000 or after 2009, and we analysed the HR of GD in the univariable and multivariable models as well as the cumulative incidence curves of GD by using Kaplan-Meier curves. This study included 13 165 and 52 660 patients with and without haemorrhoids, respectively. The mean follow-up duration was approximately 6 years. The incidence rate of GD was 1.57 and 1.13 per 1000 person-years in patients with and without haemorrhoids, respectively. The area under the cumulative incidence curve of GD in patients with haemorrhoids was higher than that of patients without haemorrhoids. The risk of GD increased by 1.39 times (95% CI 1.13 to 1.71) in patients with haemorrhoids compared with patients without haemorrhoids. In the subgroup analysis, women with haemorrhoids had a higher risk of GD (adjusted HR 1.44; 95% CI 1.13 to 1.83). Patients with haemorrhoids aged 30-39 years were more likely to develop GD (adjusted HR 1.73; 95% CI 1.18 to 2.55).”

According to the news editors, the research concluded: “The findings of this study indicate that patients with haemorrhoids may have an increased risk of GD compared with other potential confounding factors.”

For more information on this research see: Association Between Haemorrhoids and Graves’ Disease: a Retrospective Cohort Study Using Data From Taiwan’s Longitudinal Health Insurance Database. BMJ Open, 2021;11(12). BMJ Open can be contacted at: Bmj Publishing Group, British Med Assoc House, Tavistock Square, London WC1H 9JR, England. (BMJ Publishing Group - http://group.bmj.com/; BMJ Open - http://bmjopen.bmj.com/)

The news editors report that additional information may be obtained by contacting Chia-Hung Kao, China Medical University, Graduate Institute of Biomedical Sciences, College of Medicine, Taichung, Taiwan. Additional authors for this research include Shang-Rong Zhong, Chun-Cheng Liao, Hsin-Hung Chen, Chun-Hung Su and Hei-Tung Yip.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1136/bmjopen-2021-053442. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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