Niigata University Graduate School of Medical and Dental Sciences Reports Findings in Hypoparathyroidism (Actual prevalence of hypoparathyroidism after total thyroidectomy: a health insurance claims-database study): Parathyroid Diseases and Conditions – Hypoparathyroidism

2022 AUG 15 (NewsRx) -- By a News Reporter-Staff News Editor at Insurance Daily News -- New research on Parathyroid Diseases and Conditions - Hypoparathyroidism is the subject of a report. According to news reporting originating in Niigata, Japan, by NewsRx journalists, research stated, “Persistent hypoparathyroidism (hypoPT) is a major complication of total thyroidectomy. Nonetheless, previous reports may have underestimated the prevalence of hypoPT due to patient selection bias.”

The news reporters obtained a quote from the research from the Niigata University Graduate School of Medical and Dental Sciences, “We aimed to estimate the actual prevalence of persistent hypoPT after total thyroidectomy and to find predictive factors for postoperative hypoPT. This study retrospectively reviewed data from a health insurance claims-based database provided by the Japan Medical Data Center Co., Ltd. From 2009 to 2019, 2388 patients who underwent total thyroidectomy were identified using the medical procedure codes. Persistent hypoPT was defined as the prescription of active vitamin D supplements for >1 year postoperatively and the assignment of hypoPT codes. The prevalence of persistent hypoPT was estimated at two different levels: minimum and maximum estimations with or without postoperative osteoporosis and/or renal failure codes. Correlates for persistent hypoPT were investigated among several demographic and clinical variables. Of the 2388 patients, 1752 (73.4%) were women with a mean age of 45 years. The types of diseases were: benign thyroid disease (n = 235), malignant thyroid tumors (n = 1570), Graves ‘ disease (n = 558), and malignancy combined with Graves’ disease (n = 25). The minimum and the maximum estimation of the prevalence of persistent hypoPT were 15.0 and 20.3%, respectively. Multivariate logistic regression analysis showed that the malignant tumor (odds ratio, 1.8) independently correlated with persistent hypoPT. The prevalence of persistent hypoPT after total thyroidectomy estimated by the claims-based database was higher than previously recognized.”

According to the news reporters, the research concluded: “Comprehensive attempts to preserve parathyroid function, especially in malignant diseases, are essential.”

This research has been peer-reviewed.

For more information on this research see: Actual prevalence of hypoparathyroidism after total thyroidectomy: a health insurance claims-database study. Endocrine, 2022. Endocrine can be contacted at: Springer, One New York Plaza, Suite 4600, New York, Ny, United States. (Springer - www.springer.com; Endocrine - http://www.springerlink.com/content/1355-008x/)

Our news correspondents report that additional information may be obtained by contacting Takeshi Takahashi, Dept. of Otolaryngology-Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan. Additional authors for this research include Keisuke Yamazaki, Ryusuke Shodo, Yushi Ueki and Arata Horii.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1007/s12020-022-03153-1. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

The publisher of the journal Endocrine can be contacted at: Springer, One New York Plaza, Suite 4600, New York, Ny, United States.

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