New Epidemiology Study Findings Reported from Tohoku University (Relationship Between Calcium Intake and Impaired Activities of Daily Living in a Japanese Population: NIPPON DATA90)

Clinical Trials Daily

2021 FEB 23 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Daily -- Data detailed on epidemiology have been presented. According to news reporting originating from Sendai, Japan, by NewsRx correspondents, research stated, “Major reasons for long-term care insurance certification in Japan are stroke, dementia, and fracture. These diseases are reported to be associated with calcium intake.”

Our news reporters obtained a quote from the research from Tohoku University: “This study examined the association between calcium intake and impaired activities of daily living (ADL) using the data from NIPPON DATA90, consisting of representative sample of the Japanese population. A population-based nested case-control study was performed. A baseline survey was conducted in 1990, followed by ADL surveys of individuals 65 years old in 2000. Individuals with impaired ADL and selected age- and sex-matched controls were then identified. We obtained 132 pairs. Calcium intake was energy-adjusted using the residual method. The association between calcium intake and impaired ADL was examined using conditional logistic regression models. To assess the accuracy of the estimates, we conducted bootstrap analyses. The adjusted odds ratios (ORs) for impaired ADL compared with the group with a calcium intake of <476 mg/day were 0.72 (95% confidence interval [CI], 0.37-1.40) for the 476-606 mg/day group and 0.44 (95% CI, 0.21-0.94) for the 607 mg/day group in 2000 (P for linear trend = 0.03). After the bootstrap analyses, the inverse relationship unchanged (median OR per 100-mg rise in calcium intake, 0.87 [1,000 resamplings]; 95% CI, 0.76-0.97).”

According to the news editors, the research concluded: “After bootstrap analyses, calcium intake was inversely associated with impaired ADL 10 years after the baseline survey.”

For more information on this research see: Relationship Between Calcium Intake and Impaired Activities of Daily Living in a Japanese Population: NIPPON DATA90. Journal of Epidemiology, 2021,31(2):119-124. (Journal of Epidemiology - http://jeaweb.jp/english/journal/index.html). The publisher for Journal of Epidemiology is Japan Epidemiological Association.

A free version of this journal article is available at https://doi.org/10.2188/jea.JE20190234.

Our news journalists report that more information may be obtained by contacting Mana Kogure, Division of Personalized Prevention and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan. Additional authors for this research include Naho Tsuchiya, Akira Narita, Takumi Hirata, Naoki Nakaya, Tomohiro Nakamura, Atsushi Hozawa, Takehito Hayakawa, Nagako Okuda, Naoko Miyagawa, Aya Kadota, Takayoshi Ohkubo, Yoshitaka Murakami, Kiyomi Sakata, Katsuyuki Miura, Akira Okayama, Tomonori Okamura, Hirotsugu Ueshima.