New Dementia Data Have Been Reported by Researchers at Chang Gung University (Persistence and adherence to rivastigmine in patients with dementia: Results from a noninterventional, retrospective study using the National Health Insurance …)

Health & Medicine Business Daily

2019 FEB 28 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Business Daily -- Research findings on Neurodegenerative Diseases and Conditions - Dementia are discussed in a new report. According to news reporting out of Taoyuan, Taiwan, by NewsRx editors, research stated, “The objective of the study was to assess adherence and persistence of patients treated with rivastigmine versus donepezil. Persistence was calculated as the time from the first prescription date of rivastigmine/donepezil until discontinuation/medication switch/end of available data, whichever occurred first.”

Our news journalists obtained a quote from the research from Chang Gung University, “Adherence was calculated as proportion of days covered and medication possession ratio. A majority of patients persisted on 4.5 and 6 mg of rivastigmine for 429 and 468 days, respectively, versus 443 and 441 days for patients receiving 5 and 10 mg of donepezil daily, respectively. Patients who initially received 1.5 mg of oral rivastigmine required a shorter time to reach a stable dose compared with those who initiated treatment at a higher dose of rivastigmine. Patients at a stable dose of 4.5 or 6 mg of rivastigmine were observed to persist longer than those at a lower dose of rivastigmine and donepezil.”

According to the news editors, the research concluded: “Although results indicate significant difference in persistence between rivastigmine and donepezil groups, clinical significance remains undetermined.”

For more information on this research see: Persistence and adherence to rivastigmine in patients with dementia: Results from a noninterventional, retrospective study using the National Health Insurance research database of Taiwan. Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2018;5():46-51.

Our news journalists report that additional information may be obtained by contacting C.J. Chang, Graduate Institute of Clinical Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan. Additional authors for this research include T.C. Chou, C.C. Chang, T.F. Chen, C.J. Hu, J.L. Fuh, W. Wang, C.M. Chen, W. Hsu and C.C Huang.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.trci.2018.06.013. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.