National Health Insurance Service Ilsan Hospital Researchers Detail Research in COVID-19 (Development and validation of a prognostic model for early triage of patients diagnosed with COVID-19): Coronavirus – COVID-19

CDC & FDA Daily

2021 NOV 25 (NewsRx) -- By a News Reporter-Staff News Editor at CDC & FDA Daily -- Data detailed on coronavirus have been presented. According to news originating from the National Health Insurance Service Ilsan Hospital by NewsRx editors, the research stated, “We developed a tool to guide decision-making for early triage of COVID-19 patients based on a predicted prognosis, using a Korean national cohort of 5,596 patients, and validated the developed tool with an external cohort of 445 patients treated in a single institution.”

Financial supporters for this research include NATIONAL HEALTH INSURANCE SERVICE ILSANHOSPITAL.

Our news editors obtained a quote from the research from National Health Insurance Service Ilsan Hospital: “Predictors chosen for our model were older age, male sex, subjective fever, dyspnea, altered consciousness, temperature 37.5 °C, heart rate 100 bpm, systolic blood pressure 160 mmHg, diabetes mellitus, heart disease, chronic kidney disease, cancer, dementia, anemia, leukocytosis, lymphocytopenia, and thrombocytopenia. In the external validation, when age, sex, symptoms, and underlying disease were used as predictors, the AUC used as an evaluation metric for our model’s performance was 0.850 in predicting whether a patient will require at least oxygen therapy and 0.833 in predicting whether a patient will need critical care or die from COVID-19. The AUCs improved to 0.871 and 0.864, respectively, when additional information on vital signs and blood test results were also used. In contrast, the protocols currently recommended in Korea showed AUCs less than 0.75.”

According to the news editors, the research concluded: “An application for calculating the prognostic score in COVID-19 patients based on the results of this study is presented on our website ( https://nhimc.shinyapps.io/ih-psc/ ), where the results of the validation ongoing in our institution are periodically updated.”

For more information on this research see: Development and validation of a prognostic model for early triage of patients diagnosed with COVID-19. Scientific Reports, 2021,11(1):1-12. (Scientific Reports - http://www.nature.com/srep/index.html). The publisher for Scientific Reports is Nature Portfolio.

A free version of this journal article is available at https://doi.org/10.1038/s41598-021-01452-7.

Our news journalists report that additional information may be obtained by contacting Chansik An, Research Institute, National Health Insurance Service Ilsan Hospital. Additional authors for this research include Hyun Cheol Oh, Jung Hyun Chang, Seung-Jin Oh, Jung Mo Lee, Chang Hoon Han, Seong Woo Kim.