Data on Diabetes Mellitus Reported by Ji-In Lee and Colleagues (Association of blood pressure with cardio-renal events and mortality in Type 2 DM: a national health insurance database): Nutritional and Metabolic Diseases and Conditions – Diabetes Mellitus

2023 JUL 20 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Business Daily -- New research on Nutritional and Metabolic Diseases and Conditions - Diabetes Mellitus is the subject of a report. According to news reporting originating from Seoul, South Korea, by NewsRx correspondents, research stated, “The relationship of blood pressure (BP) with cardio-renal events and all-cause mortality in type 2 diabetes mellitus (T2DM) is still controversial. The objective of this study was to investigate the optimal BP target in Korean individuals with T2DM.”

Our news editors obtained a quote from the research, “Korean national health insurance system (KNHIS) database study. Data of individuals with T2DM who underwent regular health checks from January 1, 2007 to December 31, 2007 were extracted (N=1,800,073). Among them, a total of 326,593 individuals were included in the final study. The study population was divided into seven groups according to their observed systolic blood pressure (SBP) (<110, 110-119, 120-129, 130-139, 140-149, 150-159, 160-169, and 170 mm Hg) and diastolic blood pressure (DBP) (<65, 65-69, 70-74, 75-79, 80-84, 85-89, and 90 mmHg). Hazard ratios (HRs) of cardio-renal events and all-cause mortality according to BP categories were analyzed. Compared to SBP of 120-129 mm Hg and DBP of 75-79 mm Hg, SBP of 130 mm Hg and DBP of 80 mm Hg were associated with an increase in HR of major cardiovascular adverse events (MACEs). SBP of 120-129 mm Hg and DBP 75-79 mm Hg were associated with the lowest HR of all-cause mortality. Both lower BP (SBP/DBP <120/70 mm) and higher BP (SBP/DBP 130/80mm Hg) were associated with an increased HR of all-cause mortality. Contrary to MACE, the lower the SBP, the lower the HR of renal events. In patients with T2DM, the optimal cutoff value of BP associated with a lower incidence of MACEs and mortality may be 120-129 mmHg for SBP and 75-79 mm Hg for DBP.”

According to the news editors, the research concluded: “However, lower SBP may be helpful for T2DM patients with a high risk of renal disease.”

This research has been peer-reviewed.

For more information on this research see: Association of blood pressure with cardio-renal events and mortality in Type 2 DM: a national health insurance database. The Journal of Clinical Endocrinology & Metabolism, 2023. The Journal of Clinical Endocrinology & Metabolism can be contacted at: Endocrine Soc, 2055 L St NW, Suite 600, Washington, DC 20036, USA.

The news editors report that additional information may be obtained by contacting Ji-In Lee, Research Institute of The Way Healthcare, Seoul, South Korea. Additional authors for this research include Bo-Yeon Kim, Hye-Mi Lee, So Hun Kim, Eun Yeong Mo, Jang Won Son, Sihoon Lee and Sungrae Kim.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1210/clinem/dgad404. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the The Journal of Clinical Endocrinology & Metabolism is: Endocrine Soc, 2055 L St NW, Suite 600, Washington, DC 20036, USA.

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