Yonsei University Wonju College of Medicine Reports Findings in Vitiligo (Automated mass screening for comorbidities of vitiligo using the National Health Insurance database): Skin Diseases and Conditions – Vitiligo

2023 APR 11 (NewsRx) -- By a News Reporter-Staff News Editor at Information Technology Business Daily -- New research on Skin Diseases and Conditions - Vitiligo is the subject of a report. According to news reporting out of Wonju, South Korea, by NewsRx editors, research stated, “Although the study design for identifying specific disease associations using health insurance database has been well established, few studies explore unknown comorbidities. We conducted a series of automated case-control studies for all International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10) diagnostic codes (A01 to Z99) using the Korean National Health Insurance database from 2007 to 2017 to reveal undiscovered disease associations of vitiligo.”

Our news journalists obtained a quote from the research from the Yonsei University Wonju College of Medicine, “A total of 90,297 vitiligo patients and 90,297 age- and sex-matched controls without vitiligo were included, and disease associations for 1,265 relevant diagnostic codes were screened. A meta-analysis of the individual odds ratios for each ICD-10 code was performed to identify the possibility of selection bias. Finally, the association with vitiligo was significantly increased in 45 diseases and decreased in 6 diseases. We not only reaffirmed the positive correlation between vitiligo and other autoimmune diseases, but also observed associations with obsessive-compulsive disorder and melanoma. On the other hand, femur fracture showed a negative correlation. In this study, we attempted an automated mass screening and suggested a possible selection bias.”

According to the news editors, the research concluded: “In the era of large-scale databases, a systematic and comprehensive approach might be needed.”

This research has been peer-reviewed.

For more information on this research see: Automated mass screening for comorbidities of vitiligo using the National Health Insurance database. Journal of Investigative Dermatology, 2023. Journal of Investigative Dermatology can be contacted at: Elsevier Science Inc, Ste 800, 230 Park Ave, New York, NY 10169, USA. (Nature Publishing Group - http://www.nature.com/; Journal of Investigative Dermatology - http://www.nature.com/jid/)

Our news journalists report that additional information may be obtained by contacting Solam Lee, Dept. of Dermatology, Yonsei University Wonju College of Medicine, Wonju, South Korea. Additional authors for this research include Ju Hee Han, Hyun Jeong Ju, Miri Kim, Chong Won Choi and Jung Min Bae.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.jid.2023.02.031. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the Journal of Investigative Dermatology is: Elsevier Science Inc, Ste 800, 230 Park Ave, New York, NY 10169, USA.

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