Reports on Osteoporosis Findings from Quantify Research Provide New Insights (A health economic simulation model for the clinical management of…

Health & Medicine Week

Reports on Osteoporosis Findings from Quantify Research Provide New Insights (A health economic simulation model for the clinical management of osteoporosis)

By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators discuss new findings in Musculoskeletal Diseases and Conditions - Osteoporosis. According to news reporting from Stockholm, Sweden, by NewsRx journalists, research stated, "The objective was to estimate the burden of osteoporosis in Sweden based on current clinical practice and the cost-effectiveness of improvements in the management of osteoporosis over the clinical management compared to current clinical practice. Results showed that better compliance to treatment guidelines is associated with better projected outcomes and cost-savings."

Financial support for this research came from Medtronic (see also Musculoskeletal Diseases and Conditions - Osteoporosis).

The news correspondents obtained a quote from the research from Quantify Research, "The purpose of this study is to estimate the burden of osteoporosis in Sweden based on current clinical practice and the cost-effectiveness of improvements in the management of osteoporosis over the clinical management compared to current clinical practice. The analysis was carried out using a model that simulates the individual patients considered for pharmacological treatment during 1 year and their projected osteoporosis treatment pathway, quality-adjusted life years (QALYs) and costs over their remaining lifetime. All patients regardless of treatment or no treatment were simulated. Information on current management of osteoporosis in terms of patient characteristics and treatment patterns were derived from a Swedish osteoporosis research database based on national registers and patient records. Current (standard) clinical management was compared with alternative scenarios mirroring Swedish treatment guidelines. The national burden in terms of lost QALYs was estimated at 14,993 QALYs and the total economic cost at (sic)776M. Scenario analyses showed that 382-3864 QALYs could be gained at a cost/QALY ranging from cost-saving to (sic)31368, depending on the scenario. The margin of investment, i.e. the maximum amount that could be invested in the healthcare system to achieve these improvements up to the limit of the willingness to pay/QALY, was estimated at (sic)199M on a population level ((sic)3,634/patient). The analysis showed that better compliance to treatment guidelines is associated with better projected outcomes and cost-savings."

According to the news reporters, the research concluded: "From a cost-effectiveness perspective, there is also considerable room for investment to achieve these improvements in the management of osteoporosis."

For more information on this research see: A health economic simulation model for the clinical management of osteoporosis. Osteoporosis International, 2018;29(3):545-555. Osteoporosis International can be contacted at: Springer London Ltd, 236 Grays Inn Rd, 6TH Floor, London WC1X 8HL, England. (Springer - www.springer.com; Osteoporosis International - www.springerlink.com/content/0937-941x/)

Our news journalists report that additional information may be obtained by contacting E. Jonsson, Quantify Res, SE-11221 Stockholm, Sweden. Additional authors for this research include A. Hansson-Hedblom, O. Ljunggren, K. Akesson, A. Spangeus, J.A. Kanis and F. Borgstrom.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1007/s00198-017-4325-4. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Keywords for this news article include: Stockholm, Sweden, Europe, Musculoskeletal Diseases and Conditions, Metabolic Bone Diseases and Conditions, Health and Medicine, Osteoporosis, Quantify Research.