National Taiwan University Hospital Reports Findings in Stroke (Incidence of stroke among patients with polycystic kidney disease in Taiwan: a retrospective population-based cohort study using National Health Insurance Database): Cerebrovascular Diseases and Conditions – Stroke

2021 NOV 12 (NewsRx) -- By a News Reporter-Staff News Editor at Information Technology Business Daily -- New research on Cerebrovascular Diseases and Conditions - Stroke is the subject of a report. According to news reporting originating from Taipei, Taiwan, by NewsRx correspondents, research stated, “Few studies documented incidence rates of different types of stroke among patients with polycystic kidney disease (PKD). We conducted a retrospective cohort study based on the National Health Insurance (NHI) Database of Taiwan.”

Financial support for this research came from National Health Research Institutes.

Our news editors obtained a quote from the research from National Taiwan University Hospital, “The PKD cohort comprised patients aged 20 years diagnosed with PKD using inpatient claims from 1998 to 2011, excluding prior stroke. The reference cohort was established by inpatients without PKD using 1:4 frequency-matched with age, gender, and baseline comorbidities. The two cohorts were followed-up until stroke hospitalization, death, withdrawal from the NHI program, or the end of 2012. To account for competing risks of death, we used multivariable competing risks regression models to estimate sub-distribution hazard ratio (SHR) adjusted for age, gender, baseline comorbidities and end stage renal disease. 7837 PKD patients and 31211 reference subjects were followed up through 2012. A total of 955 cases of stroke were identified in the PKD cohort, including 441 ischemic stroke (IS), 289 intracranial hemorrhage (ICH), 73 subarachnoid hemorrhage (SAH) and 232 other stroke. The incidence rates of overall stroke, IS, ICH, and SAH were 21.3, 10.2, 6.8, and 1.7 per 1000 person-years, respectively. The SHR for overall stroke was 1.39 [95% confidence interval (CI) 1.28-1.50]. SAH had the highest SHR, 4.55 [95% CI 3.26-6.37], followed by ICH (1.84), other stroke (1.24), and IS (1.22). This study illustrated the incidence rates of stroke among inpatient of PKD.”

According to the news editors, the research concluded: “The PKD patients had a significantly increased risk of all kinds of stroke after adjusting baseline comorbidities.”

For more information on this research see: Incidence of stroke among patients with polycystic kidney disease in Taiwan: a retrospective population-based cohort study using National Health Insurance Database. Biomedical Journal, 2021. Biomedical Journal can be contacted at: Elsevier, Radarweg 29, 1043 Nx Amsterdam, Netherlands.

The news editors report that additional information may be obtained by contacting Li-Kai Tsai, Dept. of Neurology and Stroke Center, National Taiwan University Hospital, Taipei, Taiwan. Additional authors for this research include Lukas Jyuhn-Hsiarn Lee, Yu-Yin Chang, Jung-Der Wang and Juliana Tze-Wah Kao.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.bj.2021.10.005. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the Biomedical Journal is: Elsevier, Radarweg 29, 1043 Nx Amsterdam, Netherlands.

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