National Health Insurance Service Ilsan Hospital Researchers Further Understanding of Gastric Cancer (The Efficacy of a Novel Type of Integrated Knife for Endoscopic Submucosal Dissection in Early Gastric Cancer): Oncology – Gastric Cancer

Cancer Daily

2022 MAR 01 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Daily -- Research findings on gastric cancer are discussed in a new report. According to news reporting originating from Goyang, South Korea, by NewsRx correspondents, research stated, “This study aimed to compare the efficacy of a recently developed clear-cut knife with that of widely used knives for endoscopic submucosal dissection (ESD) in early gastric cancer (EGC). Data were collected retrospectively from the National Health Insurance Service Ilsan Hospital between May 2017 and April 2019. The study included 105 patients (108 lesions) with EGC who underwent ESD.”

Funders for this research include National Health Insurance Ilsan Hospital Award: NHIMC2019CR026.

The news journalists obtained a quote from the research from National Health Insurance Service Ilsan Hospital: “Fifty-six EGCs were dissected using an insulation-tipped diathermic knife in combination with a needle knife, while 52 EGCs were dissected using a clear-cut knife, a single device with an integrated needle and an insulated-tipped knife. Oncologic outcomes and technical success were compared between the two groups. The distribution of the tumor locations, composition of the undifferentiated types of EGCs, and the size of EGCs (14.3±8.0 vs. 16.6±7.3 mm; P=0.130) were not significantly different between the groups. The complete (98.2% vs. 94.2%; P=0.273) and curative (87.5% vs. 88.5%; P=0.878) resection rates were not statistically different. Furthermore, no significant difference between the total procedure times (39±34.1 vs. 35.7±20.1 minutes; P=0.554), areas of the dissected specimen (858.6±406.5 vs. 980.3±393.8 mm2; P=0.119) and dissected areas per minute (32.4±17.9 vs. 35.5±16.2 mm2/min; P=0.345) were noted. Regarding complications, the overall perforation rates (3.6% vs. 4.0%) and bleeding rates (3.6% vs. 8.0%) were not statistically different.”

According to the news reporters, the research concluded: “The newly developed clear-cut knife is as useful as the combination of classical knives for ESD in EGC.”

For more information on this research see: The Efficacy of a Novel Type of Integrated Knife for Endoscopic Submucosal Dissection in Early Gastric Cancer. The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2022,22(1):50-58. (The Korean Journal of Helicobacter and Upper Gastrointestinal Research - http://www.helicojournal.org). The publisher for The Korean Journal of Helicobacter and Upper Gastrointestinal Research is Yong Chan Lee.

A free version of this journal article is available at https://doi.org/10.7704/kjhugr.2021.0056.

Our news editors report that additional information may be obtained by contacting Eun Ju Choe, Division of Gastroenterology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, South Korea. Additional authors for this research include Han Ho Jeon, Yong Suk Cho, Sun Young Won, Jeong Hun Seo, Jong Won Choi, Chun Kyon Lee, Byung Kyu Park, Yong Kang Lee.