National Health Insurance Service Ilsan Hospital Reports Findings in Bone Fractures (Antibiotic use in nasal bone fracture: a nationwide population-based cohort study in Korea): Bone Diseases and Conditions – Bone Fractures

South Korea Daily Report

2021 DEC 07 (NewsRx) -- By a News Reporter-Staff News Editor at South Korea Daily Report -- New research on Bone Diseases and Conditions - Bone Fractures is the subject of a report. According to news reporting originating in Goyang, South Korea, by NewsRx journalists, research stated, “Prophylactic antibiotics are commonly used in craniofacial surgeries. Despite the low risk of surgical site infection after nasal surgery, a lack of consensus regarding the use of antibiotic prophylaxis in the closed reduction of nasal bone fractures has led to inappropriate prescribing patterns.”

The news reporters obtained a quote from the research from National Health Insurance Service Ilsan Hospital, “Through this study, we aimed to investigate the status of prophylactic antibiotic use in closed reductions of nasal bone fractures in Korea. This retrospective cohort study was conducted using data from the National Health Insurance Service-National Sample Cohort of Korea from 2005 to 2015. We analyzed the medical records of patients who underwent closed reduction of nasal bone fractures. The sex, age, region of residence, comorbidities, and socioeconomic variables of the patients were collected from the database. Factors that affect the prescription of perioperative antibiotics were evaluated using multivariate logistic regression analysis. A total of 3,678 patients (mean± standard deviation of age, 28.7± 14.9 years; 2,850 men [77.5%]; 828 women [22.5%]) were included in this study. The rate of antibiotic prescription during the perioperative period was 51.4%. Approximately 68.8% of prescriptions were written for patients who had received general anesthesia. The odds of perioperative prophylactic antibiotic use were significantly higher in patients who received general anesthesia than who received local anesthesia (odds ratio, 1.59). No difference was found in terms of patient age and physician specialty. Second-generation cephalosporins were the most commonly prescribed antibiotic (45.3%), followed by third- and first-generation cephalosporins (20.3% and 18.8%, respectively). In contrast, lincomycin derivatives and aminoglycosides were not prescribed. The findings of this study showed that there was a wide variety of perioperative antibiotic prescription patterns used in nasal bone surgeries.”

According to the news reporters, the research concluded: “Evidence-based guidance regarding the prescribing of antimicrobial agents for the closed reduction of nasal bone fractures should be considered in future research.”

This research has been peer-reviewed.

For more information on this research see: Antibiotic use in nasal bone fracture: a nationwide population-based cohort study in Korea. Archives of Craniofacial Surgery, 2021;22(5):254-259.

Our news correspondents report that additional information may be obtained by contacting Ji Hyuk Jung, Dept. of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital, Goyang, South Korea. Additional authors for this research include Yeo Reum Jeon, Joon Ho Song and Seum Chung.