Findings on Osteoarthritis Discussed by Investigators at Yonsei University (Epidemiological Study of Post-traumatic Ankle Osteoarthritis After Ankle Sprain In 195,393 Individuals Over Middle Age Using the National Health Insurance Database: a …): Musculoskeletal Diseases and Conditions – Osteoarthritis

Health & Medicine Business Daily

2022 FEB 10 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Business Daily -- Investigators publish new report on Musculoskeletal Diseases and Conditions - Osteoarthritis. According to news reporting originating in Seoul, South Korea, by NewsRx journalists, research stated, “This study aimed to determine the risk of ankle OA onset after an incidence of sprain, relative to the risk of onset in healthy population, and to investigate the effect of gender, age, BMI, and exercise on the development of ankle OA after sprain. Retrospective cohort study.”

Financial supporters for this research include Ministry of Education, National Research Foundation of Korea.

The news reporters obtained a quote from the research from Yonsei University, “Using a sample cohort dataset from 2002 to 2013 provided by the Korean National Health Insurance Sharing Service, we calculated the mean survival time and cumulative incidence rate in sprained and healthy populations using Kaplan-Meier analysis. A Cox proportional hazards model was used to analyze the adjusted hazard ratio (HR) of sprain for the development of OA with 95% confidence intervals (CIs). Adjusted HRs of gender, age, BMI, and exercise (yes/no) were analyzed in the sprained group. Among the selected population of 195,393 individuals, 40,876 (20.9%) were diagnosed with an ankle sprain, and 1543 (3.85%) of those individuals developed ankle OA. Of the 154,517 healthy individuals (79.1%), 4062 (2.66%) cases had progressed to OA. The sprained group had 46% (HR, 1.46; 95% CI, 1.38-1.55) greater rate of progression to ankle OA than did healthy individuals. In the sprain group, individuals who were female, obese, and overweight had 40% (HR, 1.40; 95% CI, 1.26-1.55), 43% (HR, 1.43; 95% CI, 1.12-1.82), and 22% (HR, 1.22; 95% CI, 1.10-1.35) higher incidence to develop ankle OA, respectively, compared to those who were male, underweight and normal. This study found that ankle sprain was a significant risk factor for a diagnosis of early OA.”

According to the news reporters, the research concluded: “Female gender and high BMI increased the incidence of ankle OA after sprain.”

This research has been peer-reviewed.

For more information on this research see: Epidemiological Study of Post-traumatic Ankle Osteoarthritis After Ankle Sprain In 195,393 Individuals Over Middle Age Using the National Health Insurance Database: a Retrospective Design. Journal of Science and Medicine in Sport, 2022;25(2):129-133. Journal of Science and Medicine in Sport can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Journal of Science and Medicine in Sport - http://www.journals.elsevier.com/journal-of-science-and-medicine-in-sport/)

Our news correspondents report that additional information may be obtained by contacting Sae Yong Lee, Yonsei University, Dept. of Physical Education, Seoul, South Korea. Additional authors for this research include Soyoung Lee and Kyeongtak Song.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.jsams.2021.08.018. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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