College of Medicine Reports Findings in Kidney Cancer (Association Between Statins and the Risk of Kidney Cancer Incidence and Mortality Using the Korean National Health Insurance Claims Database): Oncology – Kidney Cancer

Information Technology Business Daily

2022 AUG 30 (NewsRx) -- By a News Reporter-Staff News Editor at Information Technology Business Daily -- New research on Oncology - Kidney Cancer is the subject of a report. According to news reporting from Seoul, South Korea, by NewsRx journalists, research stated, “Conflicting results have been reported regarding the potential preventive effects of statins on the risk of cancer. This study investigated the associations of statin use with the incidence and mortality of kidney cancer in South Korea.”

The news correspondents obtained a quote from the research from the College of Medicine, “In this retrospective population-based cohort study using the National Health Insurance claims database, we compared patients aged 45-70 years who had used statins for at least 6 months to non-statin users matched by age and sex from 2005 to June 2013. The main outcomes were kidney cancer incidence and mortality according to statin use. Cox proportional hazard regression was used to calculate the adjusted hazard ratios (aHRs) and 95% confidence intervals (95% CIs). In the cohort of 1 008 101 people, the aHRs for the association between statin use and the outcomes were .84 (95% CI: 0.71-.99) for kidney cancer incidence and .65 (95% CI: 0.41-.98) for kidney cancer mortality. In the matched cohort of 337 578, the risk per 1000 people of cancer incidence and mortality was 1.63, 1.07, and .24, .17 in statin users and non-users, respectively. In matched cohort, the risk of kidney cancer incidence and mortality decreased, but it is not statistically significant. Also, there was no linear relationship with increased doses. Statin use might be associated with a decreased risk of kidney cancer incidence and mortality, but it showed no statistical significance.”

According to the news reporters, the research concluded: “This study was a large-scale analysis, however, further studies that are larger and multinational in scope are needed to confirm the beneficial effects of statins on survival.”

For more information on this research see: Association Between Statins and the Risk of Kidney Cancer Incidence and Mortality Using the Korean National Health Insurance Claims Database. Cancer Control, 2022;29:107327482211112.

Our news journalists report that additional information may be obtained by contacting Hyun Jung Kim, Dept. of Preventive Medicine, College of Medicine, 34973Korea University, Seoul, South Korea. Additional authors for this research include Dong-Sook Kim and Hyeong Sik Ahn.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1177/10732748221111293. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.