A Prospective Study on the”Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting”
2019 OCT 01 (NewsRx) -- By a
As a matter of record, on
Tracking Information
| Trial Identifier | NCT04135911 |
| First Submitted Date | |
| First Posted Date | |
| Results First Submitted Date | Not Provided |
| Results First Posted Date | Not Provided |
| Last Update Submitted Date | |
| Last Update Posted Date | |
| Primary Completion Date | |
| Start Date | |
| Current Primary Outcome Measures | •Diagnostic classification in hypertension [ Time Frame: 2 years ] -- Differences in diagnostic classification between workplace blood pressure and daytime ambulatory blood pressure in the classification of hypertension (masked hypertension or white coat hypertension) |
| Current Secondary Outcome Measures | •Change in different blood pressure measurement [ Time Frame: 2 years ] -- Differences in workplace blood pressure, daytime ambulatory blood pressure, home blood pressure and 24-hour ambulatory blood pressure |
| •The distribution of heart rate in young and middle-aged subjects [ Time Frame: 2 years ] -- The distribution of heart rate in young and middle-aged subjects who were dignosed with hypertension | |
| •Progression of target organ damage [ Time Frame: 2 years ] -- Differences in progression of target organ damage between controled or uncontroled subjects or between subjects with fast and slow heart rate | |
| •The development of with-coat hypertension [ Time Frame: 2 years ] -- The development of white-coat hypertension as persistent hypertension and other types of hypertension or normal blood pressure and changes in target organ damage | |
| •The proportion of masked hypertension in patients with normal high blood pressure [ Time Frame: 2 years ] -- The proportion of masked hypertension in patients with normal high blood pressure and the change in outcome after treatment intervention and changes in target organ damage | |
| Other Outcome Measures | Not Provided |
| Change History | Complete list of historical revisions of study NCT04135911 |
Descriptive Information
| Brief Title | A Prospective Study on the”Management of Hypertension in |
| Official Title | A Prospective Study on the”Management of Hypertension in |
| Brief Summary | In recent years, with the investment from government in the health management of the elderly, community management of hypertension in the elderly has made great progress in management rate and standardized management, but the management of young and middle-aged patients with hypertension is still blank. Workplace pressure measurement may be more suitable for most of the young and middle-aged patients to find high blood pressure and monitor blood pressure changes in time. However, there is not much research on workplace pressure measurement. Whether blood pressure measurement in the workplace can reduce the white coat effect, and how it relates to home blood pressure and ambulatory blood pressure is still unclear. |
| Detailed Description | Not Provided |
| Study Type | Observational [Patient Registry] |
| Study Phase | Not Provided |
| Study Design | Observational Model: Cohort |
| Time Perspective: Prospective | |
| Target Follow-Up Duration | 2 Years |
| Condition | Hypertension |
| Blood Pressure | |
| Intervention | Not Provided |
| Study Arms | Not Provided |
Recruitment Information
| Recruitment Status | Not yet recruiting |
| Estimated Enrollment | 2000 |
| Estimated Completion Date | |
| Primary Completion Date | |
| Eligibility | Inclusion Criteria: 1. Male and female sex, aged 18-65 years. 2. Three different daytime workplace blood pressure measurements meet the limits: systolic blood pressure ≥ 120 mmHg, or diastolic blood pressure ≥80 mmHg. 3. Clinically diagnosed hypertension with the use of antihypertensive drugs. 4. Willing to provide information about disease history and lifestyle. 5. Willing to receive follow-up for up to 2-3 years. 6. Sign the informed consent Exclusion Criteria: 1. Having the onset of cardiovascular and cerebrovascular diseases such as stroke, myocardial infarction or heart failure within 6 months. 2. Having a history of atrial fibrillation or frequent arrhythmia. 3. Complicating other diseases that are not suitable for the trial, such as thyroid disease with active medication, acute infectious diseases, chronic mental illness, and tumors. 4. Subject is participating in other clinical studies. |
| Sex/Gender | Sexes Eligible for Study: All |
| Ages | 18 years to 65 years |
| No | |
| Contacts | Primary contact: |
| Listed Location Countries | Not Provided |
| Removed Location Countries |
Administrative Information
| NCT Number | NCT04135911 |
| Other Study ID Numbers | PROMISE20190831 |
| Has Data Monitoring Committee | Not Provided |
| Not Provided | |
| Plan to Share Data | Not Provided |
| Plan to Share Data (IPD) Description | Not Provided |
| Collaborators | Not Provided |
| Investigators | Not Provided |
| Information Provided By | |
| Verification Date |
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