A Prospective Study on the”Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting” - Insurance News | InsuranceNewsNet

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November 1, 2019 Newswires
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A Prospective Study on the”Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting”

Insurance Daily News

2019 OCT 01 (NewsRx) -- By a News Reporter-Staff News Editor at Insurance Daily News -- Staff editors report on the newly launched clinical trial, NCT04135911, which has the following summary description: “In recent years, with the investment from government in the health management of the elderly, community management of hypertension in the elderly has made great progress in management rate and standardized management, but the management of young and middle-aged patients with hypertension is still blank. Workplace pressure measurement may be more suitable for most of the young and middle-aged patients to find high blood pressure and monitor blood pressure changes in time. However, there is not much research on workplace pressure measurement. Whether blood pressure measurement in the workplace can reduce the white coat effect, and how it relates to home blood pressure and ambulatory blood pressure is still unclear.”

As a matter of record, on October 24, 2019, NewsRx staff editors report that the available information provided by Shanghai Institute of Hypertension on this trial include:

Tracking Information

Trial Identifier NCT04135911
First Submitted Date October 21, 2019
First Posted Date October 23, 2019
Results First Submitted Date Not Provided
Results First Posted Date Not Provided
Last Update Submitted Date October 21, 2019
Last Update Posted Date October 23, 2019
Primary Completion Date September 30, 2020
Start Date October 30, 2019
Current Primary Outcome Measures •Diagnostic classification in hypertension [ Time Frame: 2 years ] -- Differences in diagnostic classification between workplace blood pressure and daytime ambulatory blood pressure in the classification of hypertension (masked hypertension or white coat hypertension)
Current Secondary Outcome Measures •Change in different blood pressure measurement [ Time Frame: 2 years ] -- Differences in workplace blood pressure, daytime ambulatory blood pressure, home blood pressure and 24-hour ambulatory blood pressure
•The distribution of heart rate in young and middle-aged subjects [ Time Frame: 2 years ] -- The distribution of heart rate in young and middle-aged subjects who were dignosed with hypertension
•Progression of target organ damage [ Time Frame: 2 years ] -- Differences in progression of target organ damage between controled or uncontroled subjects or between subjects with fast and slow heart rate
•The development of with-coat hypertension [ Time Frame: 2 years ] -- The development of white-coat hypertension as persistent hypertension and other types of hypertension or normal blood pressure and changes in target organ damage
•The proportion of masked hypertension in patients with normal high blood pressure [ Time Frame: 2 years ] -- The proportion of masked hypertension in patients with normal high blood pressure and the change in outcome after treatment intervention and changes in target organ damage
Other Outcome Measures Not Provided
Change History Complete list of historical revisions of study NCT04135911

Descriptive Information

Brief Title A Prospective Study on the”Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting”
Official Title A Prospective Study on the”Management of Hypertension in Young and Middle-aged Subjects in Enterprises Setting”
Brief Summary In recent years, with the investment from government in the health management of the elderly, community management of hypertension in the elderly has made great progress in management rate and standardized management, but the management of young and middle-aged patients with hypertension is still blank. Workplace pressure measurement may be more suitable for most of the young and middle-aged patients to find high blood pressure and monitor blood pressure changes in time. However, there is not much research on workplace pressure measurement. Whether blood pressure measurement in the workplace can reduce the white coat effect, and how it relates to home blood pressure and ambulatory blood pressure is still unclear.
Detailed Description Not Provided
Study Type Observational [Patient Registry]
Study Phase Not Provided
Study Design Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration 2 Years
Condition Hypertension
Blood Pressure
Intervention Not Provided
Study Arms Not Provided

Recruitment Information

Recruitment Status Not yet recruiting
Estimated Enrollment 2000
Estimated Completion Date September 30, 2022
Primary Completion Date September 30, 2020 (Final data collection date for primary outcome measure)
Eligibility Inclusion Criteria: 1. Male and female sex, aged 18-65 years. 2. Three different daytime workplace blood pressure measurements meet the limits: systolic blood pressure ≥ 120 mmHg, or diastolic blood pressure ≥80 mmHg. 3. Clinically diagnosed hypertension with the use of antihypertensive drugs. 4. Willing to provide information about disease history and lifestyle. 5. Willing to receive follow-up for up to 2-3 years. 6. Sign the informed consent Exclusion Criteria: 1. Having the onset of cardiovascular and cerebrovascular diseases such as stroke, myocardial infarction or heart failure within 6 months. 2. Having a history of atrial fibrillation or frequent arrhythmia. 3. Complicating other diseases that are not suitable for the trial, such as thyroid disease with active medication, acute infectious diseases, chronic mental illness, and tumors. 4. Subject is participating in other clinical studies.
Sex/Gender Sexes Eligible for Study: All
Ages 18 years to 65 years
Accepts Healthy Volunteers No
Contacts Primary contact: Yan Li, MD, PhD, +8621-64370045 ext 663201, [email protected]
Listed Location Countries Not Provided
Removed Location Countries

Administrative Information

NCT Number NCT04135911
Other Study ID Numbers PROMISE20190831
Has Data Monitoring Committee Not Provided
U.S. FDA-regulated Product Not Provided
Plan to Share Data Not Provided
Plan to Share Data (IPD) Description Not Provided
Responsible Party Yan Li, Shanghai Institute of Hypertension
Collaborators Not Provided
Investigators Not Provided
Information Provided By Shanghai Institute of Hypertension
Verification Date October 2019

(Our reports deliver fact-based news of research and discoveries from around the world.)

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