Yonsei University College of Medicine Researchers Detail New Studies and Findings in the Area of Vascular Dementia (Risks and Prognoses of Alzheimer’s Disease and Vascular Dementia in Patients With Insomnia: A Nationwide Population-Based Study)

2021 MAY 20 (NewsRx) -- By a News Reporter-Staff News Editor at Hospital & Nursing Home Daily -- Researchers detail new data in vascular dementia. According to news originating from Seoul, South Korea, by NewsRx correspondents, research stated, “This study aimed to investigate the risk and prognosis of Alzheimer’s disease (AD) and vascular dementia (VaD) in patients with insomnia using the National Health Insurance Service database covering the entire population of the Republic of Korea from 2007 to 2014.”

Funders for this research include National Research Foundation of Korea; Korea Health Industry Development Institute; Yonsei University College of Medicine.

Our news reporters obtained a quote from the research from Yonsei University College of Medicine: “In total, 2,796,871 patients aged 40 years or older with insomnia were enrolled, and 5,593,742 controls were matched using a Greedy digit match algorithm. Mortality and the rate of admission to a long-term care facility were estimated using multivariable Cox analysis. Of all patients with insomnia, 138,270 (4.94%) and 26,706 (0.96%) were newly diagnosed with AD and VaD, respectively. The incidence rate ratios for AD and VaD were 1.73 and 2.10, respectively, in patients with insomnia compared with those without. Higher mortality rates and long-term care facility admission rates were also observed in patients with dementia in the insomnia group. Known cardiovascular risk factors showed interactions with the effects of insomnia on the risk of AD and VaD.”

According to the news editors, the research concluded: “However, the effects of insomnia on the incidence of AD and VaD were consistent between the groups with and without cardiovascular risk factors. Insomnia is a medically modifiable and policy-accessible risk factor and prognostic marker of AD and VaD.”

For more information on this research see: Risks and Prognoses of Alzheimer’s Disease and Vascular Dementia in Patients With Insomnia: A Nationwide Population-Based Study. Frontiers in Neurology, 2021,12. (Frontiers in Neurology - http://frontiersin.org/neurology). The publisher for Frontiers in Neurology is Frontiers Media S.A.

A free version of this journal article is available at https://doi.org/10.3389/fneur.2021.611446.

Our news journalists report that more information may be obtained by contacting Min Seok Baek, Department of Neurology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea. Additional authors for this research include Kyungdo Han, Hyuk-Sung Kwon, Yong-ho Lee, Hanna Cho, Chul Hyoung Lyoo.

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