University Hospital Nimes Researchers Describe Advances in Sleep Apnea (Cardiovascular Events, Sleep Apnoea, and Pulmonary Hypertension in Primary Sjogren’s Syndrome: Data from the French Health Insurance Database): Respiratory Tract Diseases and Conditions – Sleep Apnea

2021 NOV 25 (NewsRx) -- By a News Reporter-Staff News Editor at Insurance Daily News -- A new study on sleep apnea is now available. According to news reporting originating from Nimes, France, by NewsRx correspondents, research stated, “Primary Sjogren’s syndrome (pSS) is an autoimmune disease, associated with a high risk of lymphoma.”

Our news correspondents obtained a quote from the research from University Hospital Nimes: “Mounting evidence suggests that cardiovascular morbidity and mortality are higher in patients with pSS, although data are heterogeneous. The aim of this study was to assess whether pSS patients are at higher risk of hospitalisation for cardiovascular events (CVEs), venous thromboembolic events (VTEs), pulmonary hypertension (PH), and sleep apnoea syndrome (SAS). Through a nationwide population-based retrospective study using the French health insurance database, we selected new-onset pSS in-patients hospitalised between 2011 and 2018. We compared the incidence of CVEs (ischemic heart diseases (IHDs), strokes, and heart failure), SAS, VTEs, and PH with an age- and sex-matched (1:10) hospitalised control group. The calculations of adjusted hazard ratios (aHR) included available confounding factors. We studied 25,661 patients hospitalised for pSS compared with 252,543 matched patients.”

According to the news reporters, the research concluded: “The incidence of hospitalisation for IHD, SAS, and PH was significantly higher in pSS patients (aHR: 1.20 (1.06-1.34); * * p* * = 0.003, aHR: 1.97 (1.70-2.28); * * p* * < 0.001, and aHR: 3.32 (2.10-5.25); * * p* * < 0.001, respectively), whereas the incidence of stroke, heart failure, and VTE was the same between groups. Further prospective studies are needed to confirm these results and to explore the pathophysiological mechanisms involved.”

For more information on this research see: Cardiovascular Events, Sleep Apnoea, and Pulmonary Hypertension in Primary Sjogren’s Syndrome: Data from the French Health Insurance Database. Journal of Clinical Medicine, 2021,10(5115):5115. (Journal of Clinical Medicine - http://www.mdpi.com/journal/jcm). The publisher for Journal of Clinical Medicine is MDPI AG.

A free version of this journal article is available at https://doi.org/10.3390/jcm10215115.

Our news editors report that more information may be obtained by contacting Radjiv Goulabchand, Internal Medicine Department, University Hospital Nimes, University of Montpellier, 30029 Nimes, France. Additional authors for this research include Camille Roubille, David Montani, Pierre Fesler, Arnaud Bourdin, Nicolas Malafaye, Jacques Morel, Erik Arnaud, Benoit Lattuca, Lucie Barateau, Philippe Guilpain, Thibault Mura.

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