Public Assistance – Paris Hospitals (AP-HP) Reports Findings in Chronic Hepatitis B Virus (Performance of Algorithms for Identifying Patients With Chronic Hepatitis B or C Infection in the French Health Insurance Claims Databases Using the ANRS …): Liver Diseases and Conditions – Chronic Hepatitis B Virus

2022 DEC 29 (NewsRx) -- By a News Reporter-Staff News Editor at Insurance Daily News -- New research on Liver Diseases and Conditions - Chronic Hepatitis B Virus is the subject of a report. According to news reporting out of Paris, France, by NewsRx editors, research stated, “The validity of algorithms for identifying patients with chronic hepatitis B or C virus (HBV or HCV) infection in claims databases has been little explored. The performance of 15 algorithms was evaluated.”

Our news journalists obtained a quote from the research from Public Assistance - Paris Hospitals (AP-HP), “Data from HBV- or HCV-infected patients enrolled between August 2012 and December 2015 in French hepatology centres (ANRS CO22 HEPATHER cohort) were individually linked to the French national health insurance system (SNDS). The SNDS covers 99% of the French population and contains health care reimbursement data. Performance metrics were calculated by comparing the viral status established by clinicians with those obtained with the algorithms identifying chronic HBV- and HCV-infected patients. A total of 14 751 patients (29% with chronic HBV and 63% with chronic HCV infection) followed-up until December 2018 were selected. Despite good specificity, the algorithms relying on ICD-10 codes performed poorly. By contrast, the multi-criteria algorithms combining ICD-10 codes, antiviral dispensing, laboratory diagnostic tests (HBV DNA or HCV RNA detection and quantification, HCV genotyping), examinations for the assessment of liver fibrosis, and long-term disease registrations were the most effective (sensitivity 0.92, 95% CI, 0.91 to 0.93 and specificity 0.96, 95% CI, 0.95 to 0.96 for identifying chronic HBV-infected patients; sensitivity 0.94, 95% CI, 0.94 to 0.94 and specificity 0.85, 95% CI, 0.84 to 0.86 for identifying chronic HCV-infected patients).”

According to the news editors, the research concluded: “The multi-criteria algorithms perform well in identifying patients with chronic hepatitis B or C infection and can be used to estimate the magnitude of the public health burden associated with hepatitis B and C in France.”

This research has been peer-reviewed.

For more information on this research see: Performance of Algorithms for Identifying Patients With Chronic Hepatitis B or C Infection in the French Health Insurance Claims Databases Using the ANRS CO22 HEPATHER Cohort. Journal of Viral Hepatitis, 2022. Journal of Viral Hepatitis can be contacted at: Wiley, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell - http://www.wiley.com/; Journal of Viral Hepatitis - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2893)

Our news journalists report that additional information may be obtained by contacting Helene Fontaine, Dept. of Hepatology, Public Assistance - Paris Hospitals (AP-HP), Hospital Cochin, Paris, France. Additional authors for this research include Laurent Lam, Nathanael Lapidus, Jonathan Bellet, Clovis Lusivika-Nzinga, Jerome Nicol, Celine Dorival, Carole Cagnot, Gilles Hejblum, Stanislas Pol, Marc Bourliere and Fabrice Carrat.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1111/jvh.13788. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Publisher contact information for the Journal of Viral Hepatitis is: Wiley, 111 River St, Hoboken 07030-5774, NJ, USA.

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