New Findings Reported from Yonsei University College of Medicine Describe Advances in Myocardial Ischemia (The triglyceride-glucose index predicts ischemic heart disease risk in Koreans: a prospective study using National Health Insurance …)

Health & Medicine Business Daily

2020 DEC 29 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Business Daily -- Investigators publish new report on myocardial ischemia. According to news reporting out of Yonsei University College of Medicine by NewsRx editors, research stated, “Ischemic heart disease (IHD) without diabetes is considered an important challenge to human health and is associated with a poor prognosis, as well as a lack of health awareness.”

Financial supporters for this research include Korean Academy of Medical Sciences.

Our news journalists obtained a quote from the research from Yonsei University College of Medicine: “We prospectively investigated the relationship between the triglyceride-glucose (TyG) index, a surrogate marker of early insulin resistance, and incident IHD risk in a large cohort of nondiabetic Korean adults using National Health Insurance Service data. We assessed 16,455 participants (8426 men and 8029 women) without diabetes using data from a health risk assessment study (HERAS) and Korea Health Insurance Review and Assessment (HIRA) data. The participants were divided into four groups according to TyG index quartiles, calculated as ln [fasting triglycerides (mg/dL) x fasting plasma glucose (mg/dL)/2]. We prospectively assessed hazard ratios (HRs) with 95% confidence intervals (CIs) for IHD using multivariate Cox proportional-hazards regression models over a 50-month period that followed the baseline survey. During the follow-up period, 322 (2.0%) participants developed IHD. HRs of IHD for TyG index quartiles 2-4 were 1.61 (95% CI 1.05-2.48), 1.85 (95% CI 1.21-2.81), and 2.29 (95% CI 1.50-3.51), respectively, after adjusting for age, sex, body mass index, smoking status, alcohol intake, and physical activity.”

According to the news reporters, the research concluded: “A higher TyG index precedes and significantly predicts future IHD among nondiabetic Koreans. Accordingly, the TyG index may be a useful measure in assessing cardiovascular risk for nondiabetic adults in the preclinical stage.”

For more information on this research see: The triglyceride-glucose index predicts ischemic heart disease risk in Koreans: a prospective study using National Health Insurance Service data. Cardiovascular Diabetology, 2020,19(1):1-8. (Cardiovascular Diabetology - http://www.cardiab.com/). The publisher for Cardiovascular Diabetology is BMC.

A free version of this journal article is available at https://doi.org/10.1186/s12933-020-01186-2.

Our news editors report that additional information may be obtained by contacting Byoungjin Park, Department of Family Medicine, Yonsei University College of Medicine, Yongin Severance Hospital. Additional authors for this research include Yong-Jae Lee, Hye Sun Lee, Dong-Hyuk Jung.