National Center for Geriatrics and Gerontology Researcher Provides New Data on Clinical Research (Isotemporal Substitution of Sedentary Behavior With Moderate to Vigorous Physical Activity Is Associated With Lower Risk of Disability: A …): Clinical Research

2022 MAY 25 (NewsRx) -- By a News Reporter-Staff News Editor at Disease Prevention Daily -- Investigators publish new report on clinical research. According to news reporting from the National Center for Geriatrics and Gerontology by NewsRx journalists, research stated, “The purpose of the study was to estimate, using an isotemporal substitution model, the effect of replacing sedentary behavior (SB) with physical activity on the incidence of disability in community-dwelling older adults. This 2-year longitudinal cohort study enrolled 3691 community-dwelling older adults (57.2% women; mean age = 74.0 [SD = 5.0] years).”

Financial supporters for this research include Research Funding For Longevity Sciences; Ncgg, Grant-in-aid For Scientific Research; Strategic Basic Research Programs Redesigning Communities For Aged Society; Japan Science And Technology Agency; Health And Labor Sciences Research Grants.

The news reporters obtained a quote from the research from National Center for Geriatrics and Gerontology: “Individuals with dementia, stroke, Parkinson disease, depression, low Mini-Mental State Examination scores, dependence on basic activities of daily living, and missing data were excluded. Physical activity and potential confounding factors were investigated as a baseline survey of disability incidence, defined by Japanese long-term care insurance certification, for 2 years in 2 regions. Physical activity data (SB, light-intensity physical activity, and moderate- to vigorous-intensity physical activity [MVPA]) were measured using triaxial accelerometers for 14 days, and daily mean time spent in each physical activity parameter was computed in increments of 10 minutes. The relationship between baseline physical activity and disability incidence adjusted for potential confounders was analyzed using multilevel Cox proportional hazards regression analyses with an isotemporal substitution model. The disability incidence rate was 3.8%, excluding individuals who could not be followed-up. Replacing 10 minutes of SB per day with MVPA was associated with a decreased disability incidence (hazard ratio = 0.870; 95% CI = 0.766-0.988), whereas no evidence was found for replacing SB with light-intensity physical activity (hazard ratio = 0.980; 95% CI = 0.873-1.10).”

According to the news editors, the research concluded: “Replacing SB with MVPA was associated with a lower risk of disability. These findings are helpful for establishing disability prevention strategies. Impact: These results suggest that feasible changes in daily behavior, such as replacing 10 minutes of SB with MVPA daily, might have a protective effect on disability incidence. Clarifying these associations is useful for developing disability prevention strategies and may help reduce the incidence of disability in community-dwelling older adults.”

For more information on this research see: Isotemporal Substitution of Sedentary Behavior With Moderate to Vigorous Physical Activity Is Associated With Lower Risk of Disability: A Prospective Longitudinal Cohort Study. Physical Therapy, 2022,102(5). The publisher for Physical Therapy is Oxford University Press (OUP).

A free version of this journal article is available at https://doi.org/10.1093/ptj/pzac002.

Our news journalists report that more information may be obtained by contacting Ippei Chiba, Department of Preventive Gerontology, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Obu, Japan. Additional authors for this research include Sangyoon Lee, Seongryu Bae, Keitaro Makino, Yohei Shinkai, Osamu Katayama, Kenji Harada, Yukari Yamashiro, Naoto Takayanagi, Hiroyuki Shimada.

ORCID is an identifier for authors and includes bibliographic information. The following is ORCID information for the authors of this research: Ippei Chiba (http://orcid.org/0000-0003-1966-3595), Keitaro Makino (http://orcid.org/0000-0001-9252-8256).

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