Findings from Mayo Clinic Has Provided New Data on Rheumatoid Arthritis (Racial Differences In Multimorbidity and Comorbidities In Rheumatoid Arthritis): Autoimmune Diseases and Conditions – Rheumatoid Arthritis

Clinical Trials Daily

2022 NOV 29 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Daily -- Investigators publish new report on Autoimmune Diseases and Conditions - Rheumatoid Arthritis. According to news reporting originating from Rochester, Minnesota, by NewsRx correspondents, research stated, “To identify differences in multimorbidity and individual comorbidities among individuals with rheumatoid arthritis (RA), separated by race and ethnicity. This case-control study within OptumLabs Data Warehouse from 2010 to 2019 matched RA cases (defined by 2 codes plus prescription of an RA drug) to non-RA controls 1:1 on age, sex, race and ethnicity, region, index date of RA, and insurance coverage duration.”

Our news editors obtained a quote from the research from Mayo Clinic, “We defined multimorbidity as the presence of >= 2 or >= 5 validated comorbidities. Logistic regression models calculated adjusted odds of multimorbidity with 95% confidence intervals (95% CIs) within each race and ethnicity. We identified 154,391 RA cases and 154,391 controls (mean age 59.6, 76% female). Black enrollees had the most multimorbidity >= 2/ >= 5 (73.1%, 34.3%); Asian enrollees had the least (52.4%, 17.3%). Adjusted odds of multimorbidity >= 2 and >= 5 in RA cases versus controls was 2.19 (95% CI 2.16-2.23) and 2.06 (95% CI 2.02-2.09), respectively. This increase was similar across race and ethnicity. However, we observed elevated occurrence of certain comorbidities by race and ethnicity versus controls (P < 0.001), including renal disease in White enrollees (4.7% versus 3.2%) and valvular heart disease in Black and White enrollees (3.2% and 2.8% versus 2.6% and 2.2%). Multimorbidity is a problem for all RA patients.”

According to the news editors, the research concluded: “Targeted identification of certain comorbidities by race and ethnicity may be a helpful approach to mitigate multimorbidity.”

This research has been peer-reviewed.

For more information on this research see: Racial Differences In Multimorbidity and Comorbidities In Rheumatoid Arthritis. Arthritis Care & Research, 2022. Arthritis Care & Research can be contacted at: Wiley, 111 River St, Hoboken 07030-5774, NJ, USA.

The news editors report that additional information may be obtained by contacting Cynthia S. Crowson, Mayo Clinic, Rochester, MN 55902, United States. Additional authors for this research include Vanessa L. Kronzer, Hayley J. Dykhoff, Maria A. Stevens, Elena Myasoedova and John M. Davis.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1002/acr.25020. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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