Dong-A University Reports Findings in Chronic Periodontitis (The risk of stroke according to statin medication compliance in older people with chronic periodontitis: an analysis using the Korea National Health Insurance Service-Senior Cohort …): Periodontal Diseases and Conditions – Chronic Periodontitis

2022 SEP 29 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Business Daily -- New research on Periodontal Diseases and Conditions - Chronic Periodontitis is the subject of a report. According to news reporting originating in Busan, South Korea, by NewsRx journalists, research stated, “We investigated the risk of stroke according to statin medication compliance in older people with chronic periodontitis. Chronic periodontitis patients were extracted from the National Health Insurance Service-Senior Cohort Database from 2002 to 2014.”

The news reporters obtained a quote from the research from Dong-A University, “Among 255,056 chronic periodontitis patients, 41,412 patients with statin prescriptions for 28 days or more were included. The study population was divided into the top 25% of medication compliance group (TSG) and the lower 25% of medication compliance group (BSG). After 1:1 propensity score matching was performed, the final number of patients in the BSG and TSG was 6,172 each. To analyze the risk of stroke, a Cox proportional hazard model was performed to calculate hazard ratios (HRs) and 95% confidence intervals (95% CIs) after adjusting for age, sex, income level, hypertension, diabetes, and Charlson comorbidity index. In the Kaplan-Meier curve, the disease-free probability was prominently lower in the BSG than in the TSG (p for log-rank= 0.001). The HR in the multivariable-adjusted model for stroke occurrence in the TSG compared to the BSG was 0.79 (95% CI, 0.67 to 0.92; p= 0.002). Subgroup analyses showed significant associations between compliance to statin medication and stroke, especially in female, people 85 years or older, and patients with comorbidities. Increasing compliance to statins may reduce stroke risk in older adults with chronic periodontitis.”

According to the news reporters, the research concluded: “Therefore, in order to increase medication compliance among older people with chronic periodontitis, it is necessary for medical staff to make efforts to provide effective medication guidance.”

For more information on this research see: The risk of stroke according to statin medication compliance in older people with chronic periodontitis: an analysis using the Korea National Health Insurance Service-Senior Cohort Database. Epidemiology and Health, 2022;44. Epidemiology and Health can be contacted at: Korean Soc Epidemiology, Dept Social & Preventive Medicine, Sungkyunkwan Univ Sch Medicine, Suwon, 16419, South Korea.

Our news correspondents report that additional information may be obtained by contacting Minkook Son, Dept. of Physiology, College of Medicine, Dong-A University, Busan, South Korea. Additional authors for this research include Seon-Rye Kim and Yu-Rin Kim.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.4178/epih.e2022055. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

The publisher of the journal Epidemiology and Health can be contacted at: Korean Soc Epidemiology, Dept Social & Preventive Medicine, Sungkyunkwan Univ Sch Medicine, Suwon, 16419, South Korea.

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