CORG LLC Researchers Provide New Insights into Reproduction and Fertility (Differences in ICSI utilization rates among states with insurance mandates for ART coverage): Life Science Research – Reproduction and Fertility

2021 DEC 22 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Policy and Law Daily -- Fresh data on reproduction and fertility are presented in a new report. According to news reporting originating from the CORG LLC by NewsRx correspondents, research stated, “Assisted reproductive technology (ART) insurance mandates promote more selective utilization of ART clinic resources including intracytoplasmic sperm injection (ICSI). Our objective was to examine whether ICSI utilization differs by state insurance mandates for ART coverage and assess if such a difference is associated with male factor, preimplantation genetic testing (PGT), and/or live birth rates.”

The news reporters obtained a quote from the research from CORG LLC: “In this retrospective analysis of the Centers for Disease Control (CDC) data from 2018, ART clinics in ART-mandated states (n = 8, AR, CT, HI, IL, MD, MA, NJ, RI) were compared individually to one another and with non-mandated states in aggregate (n = 42) for use of ICSI, male factor, PGT, and live birth rates. ANOVA was used to evaluate differences between ART-mandated states and non-mandated states. Individual ART-mandated states were compared using Welch t-tests. Statistical significance was determined by Bonferroni Correction. There were significant differences in ICSI rates (%, mean ± SD) between MA (53.3 ± 21.3) and HI (90.7 ± 19.6), p = 0.028; IL (86.5 ± 18.7) and MA, p = 0.002; IL and MD (57.2 ± 30.8), p = 0.039; IL and NJ (62.0 ± 26.8), p = 0.007; between non-mandated states in aggregate (79.9 ± 19.9) and MA, p = 0.006, and NJ (62.0 ± 26.8), p = 0.02. Male factor rates of HI (65.8 ± 16.0) were significantly greater compared to CT (18.8 ± 8.7), IL (26.0 ± 11.9), MA (26.9 ± 6.6), MD (29.3 ± 9.9), NJ (30.6 ± 17.9), and non-mandated states in aggregate (29.7 ± 13.7), all p < 0.0001. No significant differences were reported for use of PGT and/or live birth rates across all age groups regardless of mandate status.”

According to the news editors, the research concluded: “ICSI use varied significantly among ART-mandated states while demonstrating no differences in live birth rates. These data suggest that the prevalence of male factor and the presence of a state insurance mandate are not the only factors influencing ICSI use. It is suggested that other non-clinical factors may impact the rate of ICSI utilization in a given state.”

For more information on this research see: Differences in ICSI utilization rates among states with insurance mandates for ART coverage. Reproductive Biology and Endocrinology, 2021,19(1):1-6. (Reproductive Biology and Endocrinology - http://www.rbej.com/). The publisher for Reproductive Biology and Endocrinology is BMC.

A free version of this journal article is available at https://doi.org/10.1186/s12958-021-00856-4.

Our news journalists report that more information may be obtained by contacting Pavel Zagadailov, Clinical Outcomes Research Group, CORG LLC. Additional authors for this research include Kyung S. Cho, David B. Seifer.

(Our reports deliver fact-based news of research and discoveries from around the world.)