AP Top Business News at 4:13 p.m. EST

Major outage at Amazon disrupts businesses across the US

Publix heiress known for philanthropy dies in Florida at 65

UK: Omicron spreading quickly; Time to work from home again

Flood insurance costs rise in areas once deemed lower risk

Serbia moves to defuse protests over Rio Tinto lithium mine

Pfizer says COVID booster offers protection against omicron

Defense team rests in Elizabeth Holmes fraud trial

Senate aims to reject Biden's vaccine mandate for businesses

Explainer: What caused Amazon's outage? Will there be more?

MacKenzie Scott won't say how much she's giving 'this time'