Air pollution-related hospitalization for chest pain, heart attack differed by seasons: American Heart Association

2023 NOV 16 (NewsRx) -- By a News Reporter-Staff News Editor at Insurance Daily News -- Research Highlights:

Embargoed until 4 a.m. CT/5 a.m. ET, Monday, Nov. 6, 2023

DALLAS, Nov. 6, 2023 - Short-term increases in fine particulate air pollution (PM2.5) during the summer and winter months in a mountain valley region of Utah were associated with increased health care visits for heart attack and unstable chest pain; however, the risk for each cardiac event differed by season, according to a preliminary study to be presented at the American Heart Association’s Scientific Sessions 2023. The meeting, to be held Nov. 11-13, in Philadelphia, is a premier global exchange of the latest scientific advancements, research and evidence-based clinical practice updates in cardiovascular science.

This study compared hospital visits for heart attack and unstable chest pain in a mountain valley of Utah during spikes in PM2.5 due to summertime wildfire smoke versus rising levels of PM2.5 during winter inversions - a weather phenomenon where a mix of cold and warm fronts trap air pollution from motor vehicles, factory emissions and other human sources.

“Summertime wildfire smoke does not cause the PM2.5 to rise as much as pollution from human sources during the winter inversions. However, the biological response to the particulate matter that is produced by wildfire smoke has been shown to be different from the response of PM2.5 produced by other sources, such as cars and businesses,” said lead study author Benjamin D. Horne, Ph.D., M.P.H., FAHA, director of cardiovascular and genetic epidemiology for Intermountain Health at the Intermountain Medical Center Heart Institute in Salt Lake City, Utah.

Previous research has linked air pollution with seeking same-day treatment for sudden, life-threatening heart conditions. This study examined heart attack and unstable chest pain separately.

“With a heart attack, you feel crushing chest pain, have difficulty breathing and symptoms where you call for an ambulance and go to the hospital right away,” Horne explained. “With unstable chest pain, people experience pain when they are at rest or doing low-intensity physical activity. They can still function and may stay home for a week or so thinking about it. When symptoms don’t go away, they decide to seek medical attention, sometimes up to two weeks after symptoms began.”

“Interestingly, in the summertime when PM2.5 rose, the data indicates people did not feel the need for hospitalization for heart attacks, but there was an immediate awareness of the need for hospitalization for unstable chest pain,” he said.

PM2.5 levels were measured at air quality monitoring stations along a valley region in Utah known as the Wasatch Front. PM2.5 spikes in both seasons were then cross-referenced with health records for people admitted to hospitals in the region. The analysis evaluated pollution on the day of admission as well as pollution two weeks prior to hospitalization. These data were compared to days in the same month when people were not admitted to the hospital.

The study found:

“During the summertime, health care professionals should be aware of increased risks of chest pain brought on from wildfire smoke,” Horne said. “If someone describes chest pain, it may be due to wildfire smoke, and they should go to the hospital as soon as possible.”

Horne added, the study results raise two questions that need to be explored: is there a difference between the composition of fine particulate pollution from wildfire smoke and the airborne pollution from human sources that spikes during the winter inversion season, and is there a behavioral component that leads people with chest pain to wait for up to two weeks to go to the hospital during a winter inversion, yet they go to the hospital immediately in the summer?

“The public should be aware, especially if they have chronic health conditions, that when wildfire smoke elevates PM2.5 levels, they should limit outdoor physical activities and exercise indoors,” he said. “When you exercise, you increase the amount of air you are inhaling, so exercising outdoors leads to increased levels of air pollution inside your body. If you are taking medications such as blood thinners, or medications for blood pressure, Type 2 diabetes or cholesterol, be sure to take them on days of elevated PM2.5 levels because they can reduce risk for heart attack and unstable angina.”

Study details:

In a 2020 scientific statement and a 2020 policy statement, the American Heart Association details the latest science about air pollution exposure and the individual, industrial and policy measures to reduce the negative impact of poor air quality on cardiovascular health.

“Air pollution is widely recognized as a significant contributor to cardiovascular disease and death and one we can modify by reducing exposure. Reversing the negative impacts of poor air quality on cardiovascular health is essential,” said Joel D. Kaufman, M.D., M.P.H., FAHA, a professor of environmental and occupational health sciences, professor of epidemiology and professor of medicine - general internal medicine at the University of Washington in Seattle, and chair of the writing group for the Association’s 2020 policy statement “Guidance to Reduce Cardiovascular Burden of Ambient Air Pollutants.”

While this study observed risks associated with hospital visits for heart attack and unstable chest pain during spikes of air pollution, individual data on pollution exposure was not available, which limits the interpretation of the findings.

Co-authors, disclosures and funding sources are listed in the abstract. The study was conducted in collaboration with Horne’s colleagues at Stanford University and Harvard University. The National Institutes of Health funded this study.

Statements and conclusions of studies that are presented at the American Heart Association’s scientific meetings are solely those of the study authors and do not necessarily reflect the Association’s policy or position. The Association makes no representation or guarantee as to their accuracy or reliability. Abstracts presented at the Association’s scientific meetings are not peer-reviewed, rather, they are curated by independent review panels and are considered based on the potential to add to the diversity of scientific issues and views discussed at the meeting. The findings are considered preliminary until published as a full manuscript in a peer-reviewed scientific journal.

The Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and biotech companies, device manufacturers and health insurance providers and the Association’s overall financial information are available here.

Additional Resources:
Keywords for this news article include: American Heart Association, Cardio Device, Cardiology, Cardiovascular, Cardiovascular Research, Chest Pain, Epidemiology, Genetics, Health and Medicine, Heart Attack, Heart Disorders and Diseases, Hospitals, Medical Devices, Risk and Prevention.

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