Adults younger than 40 with ideal heart health had lower heart disease, stroke, and kidney disease risk

Research Highlights:

• A study of nearly 4 million young adults under age 40 in South Korea found that those who had ideal cardiovascular health were nearly two-thirds less likely to develop heart disease, stroke and/or kidney disease during a 12-year follow-up period.
• Adults who had low heart health scores at study baseline in 2009-2010 but improved their cardiovascular health thereafter also had a reduced risk of heart disease, stroke or kidney disease compared to people with persistent low heart health scores.

Embargoed until 10:30 a.m. CT/11:30 a.m. ET, Thursday, March 21, 2024

(NewMediaWire) - March 21, 2024 - CHICAGO -- An analysis of health data for nearly 4 million young adults in Korea found that those who had ideal cardiovascular health had about a 65% lower risk of developing heart disease, stroke or kidney disease later in life compared to people with low heart health scores, according to preliminary research to be presented at the American Heart Association's Epidemiology and Prevention Lifestyle and Cardiometabolic Scientific Sessions 2024, March 18- 21, in Chicago. The meeting offers the latest science on population-based health and wellness and implications for lifestyle.

In a 2023 scientific statement and presidential advisory, the American Heart Association highlighted the link between heart disease and chronic kidney disease and the importance of improving cardiovascular health to prevent them.

"Cardiovascular disease is deadly, and kidney disease is quite common, even among younger adults," said lead study author Hokyou Lee, M.D., Ph.D., an associate professor of preventive medicine at Yonsei University College of Medicine in Seoul, South Korea. "These two diseases should be prevented together because they often coexist or increase the likelihood of one another. However, the importance of ideal heart health behaviors and factors in young adults have often been overlooked due to their lower short-term risk of cardiovascular and kidney diseases."

In this study, researchers reviewed data from the 2009-2010 Korean National Health Screening program to explore how cardiovascular health during young adulthood affects the risk of developing heart disease, stroke and kidney disease later in life. Participants' heart health was assessed and scored using the three modifiable lifestyle behaviors and three health measures: being physically active, maintaining a healthy weight and quitting tobacco and blood pressure, cholesterol and blood sugar, from the American Heart Association's Life's Simple 7 metrics. (Note: In 2022, sleep health was added to the seven metrics in the Association's new Life's Essential 8 measures for optimal cardiovascular health.)

The analysis found:

• Young adults with perfect heart health scores at enrollment had a 65% lower risk of developing cardiovascular or kidney disease during the 12-year follow-up compared to people with zero ideal cardiovascular health metrics. Note: In this study, a perfect heart health score was 6 out of 6 because a measure of diet was not available for participants.
• The risk of developing cardiovascular or kidney disease decreased gradually with higher heart health scores. 
• People whose scores improved from low to high during follow-up also had a lower risk of developing cardiovascular or kidney disease compared to people who had consistently low heart health scores. 

"Less than 1% of the young adults had ideal heart health scores at the beginning of the study, and, unfortunately, about half of those with perfect or near-perfect cardiovascular health eventually had lower heart health scores within a few years. However, fewer of the young adults with perfect or near-perfect cardiovascular health whose scores decreased experienced cardiovascular and kidney diseases than young adults who began with low heart health and remained that way," Lee said. "Our study highlights the importance of achieving ideal cardiovascular health during young adulthood and maintaining or improving it throughout life. More effort is needed to raise awareness among young adults about implementing and maintaining heart-healthy lifestyle behaviors early in life to help them live longer, healthier lives."

Study background information:

• The study included 3,836,283 adults in South Korea who did not have a history of cardiovascular or kidney disease. 
• Participants self-identified as female (38.2%) and male (62.8%).
• Participants were ages 20-39 years old, with a median age of 31 at the beginning of the study.

The study's limitations included that it did not use the new Life's Essential 8 health metrics to define cardiovascular health. In addition, dietary information about participants was not available, and the study included only people living in South Korea, which limits the generalizability of the study's findings to other populations.

"The findings underscore the importance of early awareness of risk factors and intervention and the adoption of healthy lifestyle behaviors in young adulthood to prevent cardiovascular and kidney diseases later in life. Moreover, the research indicates that even individuals with initially low heart health scores who improved their cardiovascular health over time experienced a reduced risk of diseases compared to those with persistently low scores. This highlights the potential for positive health outcomes through lifestyle modifications," said

Monica C. Serra, Ph.D., an associate professor and research investigator in the department of medicine in the Division of Geriatrics, Gerontology & Palliative Medicine and the Sam and Ann Barshop Institute for Longevity and Aging Studies at UT Health San Antonio in San Antonio, Texas. Serra is co-chair of the program committee of EPI Lifestyle Scientific Sessions 2024.

"The use of the American Heart Association's Life's Simple 7 metrics, including modifiable behaviors such as physical activity, weight management and tobacco cessation, along with biometric measures like blood pressure, cholesterol and blood sugar, provides a comprehensive assessment of heart health. It is noteworthy that the study did not include dietary components, and the addition of sleep health in the Association's new Life's Essential 8 was acknowledged," she said. "Overall, the research contributes valuable evidence to the importance of cardiovascular health maintenance in young adulthood for long-term disease prevention."

Co-authors, their disclosures and funding sources are listed in the abstract.

Statements and conclusions of studies that are presented at the American Heart Association's scientific meetings are solely those of the study authors and do not necessarily reflect the Association's policy or position. The Association makes no representation or guarantee as to their accuracy or reliability. Abstracts presented at the Association's scientific meetings are not peer-reviewed, rather, they are curated by independent review panels and are considered based on the potential to add to the diversity of scientific issues and views discussed at the meeting. The findings are considered preliminary until published as a full manuscript in a peer-reviewed scientific journal.

The Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and biotech companies, device manufacturers and health insurance providers and the Association's overall financial information are here.

Additional Resources:

The American Heart Association's EPI Lifestyle Scientific Sessions 2024 is the world's premier meeting dedicated to the latest advances in population-based science. The 2024 meeting is in-person only, Monday through Thursday, March 18-21, at the Hilton Chicago. The primary goal of the meeting is to promote the development and application of translational and population science to prevent heart disease and stroke and foster cardiovascular health. The sessions focus on risk factors, obesity, nutrition, physical activity, genetics, metabolism, biomarkers, subclinical disease, clinical disease, healthy populations, global health and prevention-oriented clinical trials. The Councils on Epidemiology and Prevention and Lifestyle and Cardiometabolic Health (Lifestyle) jointly planned the EPI Lifestyle Scientific Sessions 2024. Follow the meeting on Twitter at #EPILifestyle24.

About the American Heart Association

The American Heart Association is a relentless force for a world of longer, healthier lives. We are dedicated to ensuring equitable health in all communities. Through collaboration with numerous organizations, and powered by millions of volunteers, we fund innovative research, advocate for the public's health and share lifesaving resources. The Dallas-based organization has been a leading source of health information for a century. During 2024 - our Centennial year - we celebrate our rich 100-year history and accomplishments. As we forge ahead into our second century of bold discovery and impact, our vision is to advance health and hope for everyone, everywhere. Connect with us on heart.org, Facebook, X or by calling 1-800-AHA-USA1.

For Media Inquiries and AHA Expert Perspective:

AHA Communications & Media Relations in Dallas: 214-706-1173; [email protected]

John Arnst: [email protected], 214-706-1060

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and stroke.org