Renowned immunologist and oncologist Carl June receives $1 million Sanford Lorraine Cross Award
"This was an amazing event and an extraordinary group of finalists, so it's an honor and a thrill to be receiving this award," said
T cells are like the body's security guards, recognizing harmful intruders and triggering an immune response. The 2021 winner of the Sanford Lorraine Cross Award,
This therapy is now named KYMRIAH by Novartis and is FDA-approved to treat acute lymphoblastic leukemia (ALL).
In 2010, June and Levine treated their first patient – a retired 65-year-old corrections officer named
A second patient,
The story of
"
"Today this continues as we honor
While traditional awards in the medical sciences focus on the significance of the contribution of a researcher or clinician, the Sanford Lorraine Cross Award celebrates the role that the award candidate has played in bringing a new emerging transformative medical innovation across the finish line to patients, and their efforts in overcoming challenges, forging collaborations, and ensuring a successful outcome.
"By recognizing an innovation now, we can further propel research and discovery to ensure a transformative impact will be felt as soon as possible," said
"Innovation is not easy, but it is essential if we wish to maximize our impact for the patients and communities we serve," said
Finalists for the Sanford Lorraine Cross Award are determined through a rigorous selection process that uses machine learning to identify innovative areas of discovery and breakthrough science. The candidate selection is then focused on the areas with the most promising transformative potential for patients. An interdisciplinary scientific advisory board narrowed down the top areas of innovation. The individuals who have made the greatest contribution in these three areas are then identified as the finalists.
Two other finalists for this year's
- Dr.
Mark Denison ofVanderbilt University who has studied coronaviruses since the 1980s. In 2007, his lab discovered that coronaviruses have a protein that acts as a powerful proofreader during replication, meaning that the virus can self-correct errors in its RNA sequence; and - Dr.
Michael Welsh of theUniversity of Iowa , a pulmonary physician who wanted to know how human airways work, particularly how salt ions move across the airway wall. This led him to study cystic fibrosis (CF), an inherited disease that causes lifelong vulnerability to destructive lung infections and an early death.
The award is named after the Cross of Lorraine, a global symbol first chosen as emblematic for those who took action against disease in 1902 at the
The Sanford Lorraine Cross Award is supported in perpetuity through an endowment established by donors to the
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