Data on Tropical Medicine Reported by M. Lewin and Co-Researchers (Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment…

Data on Tropical Medicine Reported by M. Lewin and Co-Researchers (Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies)

By a News Reporter-Staff News Editor at Pharma Business Week -- Data detailed on Health and Medicine - Tropical Medicine have been presented. According to news originating from Corte Madera, California, by NewsRx correspondents, research stated, "The cost-effectiveness of the standard of care for snakebite treatment, antivenom, and supportive care has been established in various settings. In this study, based on data from South Indian private health-care providers, we address an additional question: 'For what cost and effectiveness values would adding adjunct-based treatment strategies to the standard of care for venomous snakebites be cost-effective?' We modeled the cost and performance of potential interventions (e.g., pharmacologic or preventive) used adjunctively with antivenom and supportive care for the treatment of snakebite."

Our news journalists obtained a quote from the research, "Because these potential interventions are theoretical, we used a threshold cost-effectiveness approach to explore this forward-looking concept. We examined economic parameters at which these interventions could be cost-effective or even cost saving. A threshold analysis was used to examine the addition of new interventions to the standard of care. Incremental cost-effectiveness ratios were used to compare treatment strategies. One-way, scenario, and probabilistic sensitivity analyses were conducted to analyze parameter uncertainty and define cost and effectiveness thresholds. Our results suggest that even a 3% reduction in severe cases due to an adjunct strategy is likely to reduce the cost of overall treatment and have the greatest impact on cost-effectiveness. In this model, for example, an investment of $10 of intervention that reduces the incidence of severe cases by 3%, even without changing antivenom usage patterns, creates cost savings of $75 per individual."

According to the news editors, the research concluded: "These findings illustrate the striking degree to which an adjunct intervention could improve patient outcomes and be cost-effective or even cost saving."

For more information on this research see: Snakebite: An Exploratory Cost-Effectiveness Analysis of Adjunct Treatment Strategies. American Journal of Tropical Medicine and Hygiene, 2018;99(2):404-412. American Journal of Tropical Medicine and Hygiene can be contacted at: Amer Soc Trop Med & Hygiene, 8000 Westpark Dr, Ste 130, Mclean, VA 22101, USA (see also Health and Medicine - Tropical Medicine).

The news correspondents report that additional information may be obtained from M. Lewin, Ophirex Inc., Corte Madera, CA, United States. Additional authors for this research include S.P. Samuel, T.C. Bulfone, C.S. Raj, B.J. Herzel and J.G. Kahn.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.4269/ajtmh.17-0922. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

Keywords for this news article include: Corte Madera, California, United States, North and Central America, Tropical Medicine, Health and Medicine, Biotechnology Companies, Drugs and Therapies, Business.

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