HealthCare Briefing for Advancements in Personalized Medicines and Diagnostic Studies – New Appointment to Company’s Scientific Advisory Board

CORAL SPRINGS, Florida, May 22, 2014 /PRNewswire/ --

Healthcare companies' acquisitions, innovative therapies and state-of-the-art detection platforms making progress in sector: ImmunoClin Corporation (OTCBB: IMCL), Express Holding Company (NASDAQ: ESRX), RXi Pharmaceuticals Corporation (NASDAQ: RXII), Sarepta Therapeutics, Inc. (NASDAQ: SRPT) and Isis Pharmaceuticals, Inc. (NASDAQ: ISIS)

ImmunoClin Corporation (OTCQB: IMCL) is a U.S. healthcare company specializing in personalized medicine. ImmunoClin's DACTELLIGENCE™ technology is a newly patented concept in bio-sensing with a potential to challenge state-of-the-art detection platforms in multiple diagnostic fields. DACTELLIGENCE™ is expected to deliver pure electronic point-of-care devices capable of rapid detection while simultaneously processing data. The Company is pleased to welcome Mr. Railton Frith, an inventor of DACTELLIGENCE technology, to the Company's Scientific Advisory Board.

"Given the advancements made in the science and discovery of novel electronic and medical technologies, we are pleased to enlist Mr. Frith's expertise to join the race to revolutionize smart, electronic bio-sensing which holds incredible potential to benefit patients throughout the globe," said Mr. J. Scott Munro, CFO of ImmunoClin Corporation.

To read the full IMCL press release, please click here: http://finance.yahoo.com/news/immunoclin-corporation-imcl-announces-appointment-111200716.html

Mr. Frith led the team of professionals that designed the DACTELLIGENCE™ technology and has recently assigned his portion of the ownership to ImmunoClin. He was a founding member of the pioneering network company Zynar/Nestar Systems formed in the Silicon Valley by the Rank Organization.

Express Holding Company (NASDAQ: ESRX) provides a range of pharmacy benefit management (PBM) services primarily in the United States and Canada. The company offers healthcare management and administration services on behalf of its clients. It operates in two segments, PBM and Other Business Operations. The company's PBM services comprise retail network pharmacy administration; home delivery pharmacy; benefit design consultation; drug utilization review; drug formulary management; clinical solutions to improve health outcomes; an array of Medicare Part D, Medicaid, and health insurance marketplace; specialty pharmacy services, such as the distribution of fertility pharmaceuticals that require special handling or packaging; bio- pharmaceutical services, including reimbursement and logistics solutions; group purchasing organization administration; and consumer health and drug information services. On Wednesday, ESRX closed up 1.01% on over 5.1 million shares traded.

RXi Pharmaceuticals Corporation (NASDAQ: RXII), a biotechnology company focused on discovering, developing and commercializing innovative therapies addressing major unmet medical needs using RNA-targeted technologies, today announced that it received the Notice of Allowance from the United States Patent and Trademark Office on its novel, self-delivering RNAi platform (sd-rxRNA®). The patent, titled "Reduced Size Self-Delivering RNAi Compounds", broadly covers both the composition and methods of use of RXi's self-delivering platform technology. The patent, once issued, will be scheduled to expire in 2029. This core patent, within RXi's intellectual property portfolio, is the foundation for RXI's self-delivering platform. The patent broadly protects RXi's sd-rxRNA technology, which facilitates the delivery of RNAi compounds to tissues and cells of interest in the absence of a delivery vehicle.

Sarepta Therapeutics, Inc. (NASDAQ: SRPT), a developer of innovative RNA-based therapeutics, recently announced an agreement to acquire a multifunctional manufacturing facility on 26 acres of land in Massachusetts. Sarepta intends to use the facility to manufacture investigational exon skipping therapies for Duchenne muscular dystrophy (DMD). The transaction comprises approximately $25 million in acquisition costs and planned enhancements, and is expected to close in July subject to conditions and extensions in the agreement. "This strategic acquisition complements our existing internal manufacturing capability and global network of suppliers," said Chris Garabedian, president and chief executive officer of Sarepta Therapeutics. "While we scale up to address the potential U.S. commercial demand for our lead product candidate eteplirsen in the event of an approval next year, the addition of internal resources will enhance our ability to advance the development of our broader exon skipping platform and explore the potential of our technology platform in other therapeutic areas."

Isis Pharmaceuticals, Inc. (NASDAQ: ISIS) recently announced positive top-line data from a Phase 2 comparator-controlled study evaluating the incidence of venous thrombolic events (VTE) in patients treated with ISIS-FXI_Rx undergoing total knee replacement surgery, or total knee arthroplasty (TKA). ISIS-FXI_Rx inhibits the production of Factor XI, a coagulation factor that plays a key role in thrombosis. In this study with a data cutoff of May 7, 2014, ISIS-FXI_Rx-treated patients experienced a dose-dependent decrease in VTEs. Patients treated with 300 mg of ISIS-FXI_Rx experienced a seven-fold (pRx had comparable incidence of VTEs compared to patients treated with enoxaparin. Patients treated with ISIS-FXI_Rx and enoxaparin experienced a very low rate of bleeding with ISIS-FXI_Rx-treated patients experiencing numerically fewer bleeding events compared to patients treated with enoxaparin. Isis plans to report the full data at an upcoming scientific meeting.

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