Sources Sought Notice - Immunologic Function in Autism and Related Conditions

Federal Information & News Dispatch, Inc.

Notice Type: Sources Sought Notice

Posted Date: 06-AUG-14

Office Address: Department of Health and Human Services; National Institutes of Health; National Institute on Drug Abuse, Station Support/Simplified Acquisitions; 31 Center DriveRoom 1B59 Bethesda MD 20892

Subject: Immunologic Function in Autism and Related Conditions

Classification Code: B - Special studies and analysis - not R&D

Solicitation Number: HHS-NIH-NIDA-SSSA-SBSS-FY14-562

Contact: Paul C. Marsalese, Contract Specialist , Phone 3015941971, Email [email protected]

Setaside: N/AN/A

Place of Performance (address): Bethesda, MD

Place of Performance (zipcode): 20814

Place of Performance Country: US

Description: Department of Health and Human Services

National Institutes of Health

National Institute on Drug Abuse, Station Support/Simplified Acquisitions

Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, MD 20892. Introduction: This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations.

The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.

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This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only.

North American Industry Classification System (NAICS) CODE: The NAICS code applicable to this requirement is 611310 - Colleges, Universities, and Professional Schools - and the associated small business size standard of $25.5 million dollars.

Background Information: The National Institute of Mental Health (NIMH), Section on Behavioral Pediatrics in the Pediatrics and Developmental Neuroscience Branch (PDN), conducts clinical research on a variety of childhood behavioral problems including research to identify both biological and clinical factors which influence the onset and expression of behavioral symptoms and to develop more effective treatment and prevention strategies for childhood disorders. Currently, PDN's research is focused primarily on autism spectrum disorders (including autism, PDD-NOS and Aspergers disorder) and obsessive compulsive disorder, including the PANS and PANDAS subtypes.

Purpose and Objectives for the Acquisition: This potential contract will allow a board certified pediatrician and rheumatologist to consult on immunological aspects of Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus (PANDAS/PANS) and autism research. The individual will provide expertise on three areas that are critical to research on acute onset Obsessive Compulsive Disorder (OCD), PANDAS/PANS. Specifically he/she will provide expertise needed to do HLA subtyping, analyze antinuclear antibody abnormalities, and determine disease mechanisms for PANDAS/PANS and autoimmune encephalitis. The physician will provide clinical expertise as a blinded rater of behavioral descriptions and measure for individuals with these disorders. The contractor will analyze clinical and biological data from subjects with acute-onset OCD and will write and edit manuscripts for submission and will serve as a co­ author on additional papers.

Contractor Requirements (Scope of Work): The contractor requirements may include, but are not limited to the following:

* PANDAS Long Term Outcome Project. Data analysis, interpretation and write up of results. * HLA Project for NIMH/Stanford PANS/PANDAS Cohort -emoll patients for long­ term outcome study, genetic study and antibody profiling. * Develop Treatment Guidelines with the PANS/PANDAS Research Consortium, publish and distribute. * Create Screening Tools and Treatment Guideline Flow-Charts for Pediatricians, Emergency Rooms and Urgent Care Centers to be distributed to the greater medical community. * Create EPIC Computer Templates for evaluating and managing PANS/PANDAS Patients including patient questionnaires to be distributed to the greater medical community. * Work with PPN to post diagnostic and treatment guidelines and periodically review content to check for accuracy. * Work with NIMH to establish biorespository and databank for PANDAS/PANS/Sydenham chorea. * Work with advocacy groups and policy leaders to reform/create laws that allow patients to pursue insurance coverage for the medical treatment of PANS/PANDAS.

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Anticipated period of performance: It is anticipated that the period of performance for this requirement will be one (1) twelve-month base period with zero (0) option periods.

Capability Statement: Contractors that believe they possess the ability to provide the required services should submit documentation of their ability to meet the project requirements to the Contract Specialist. Contractors should also provide their Company Name, DUNS number, Physical Address, and Point of contact Information.

Interested organizations are required to identify their type of business, applicable North American Industry Classification System Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number.

All capability statements sent in response to this Sources Sought Notice must be submitted electronically (via email) to Paul Marsalese, Contract Specialist, at [email protected] in MS Word format within 7 calendar days of the date of this announcement. All responses must be received by the specified due date and time in order to be considered.

Note: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After review of the responses received, pre-solicitation and solicitation notices may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. The solicitation release date is pending. The Government intends to negotiate a fixed-price contract.


Copyright:(c) 2013 Federal Information & News Dispatch, Inc.

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